Stability study of unmodified siRNA and relevance to clinical use. (Q39317131)

11 September 2017

Stability study of unmodified siRNA and relevance to clinical use. (English)

1 reference

11 September 2017

Brian H Johnston

8

0 references

Christopher H. Contag

object named as

Christopher H Contag

7

0 references

author name string

Robyn P Hickerson

1

1 reference

11 September 2017

Alexander V Vlassov

2

1 reference

11 September 2017

Qian Wang

3

1 reference

11 September 2017

Devin Leake

4

1 reference

11 September 2017

Heini Ilves

5

1 reference

11 September 2017

Emilio Gonzalez-Gonzalez

6

1 reference

11 September 2017

Roger L Kaspar

9

1 reference

11 September 2017

1 December 2008

1 reference

11 September 2017

1 reference

11 September 2017

18

1 reference

11 September 2017

4

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11 September 2017

345-354

1 reference

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Delivering silence: advancements in developing siRNA therapeutics.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Delivery vehicles for small interfering RNA in vivo

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Interfering with disease: a progress report on siRNA-based therapeutics

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Strategies for silencing human disease using RNA interference

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

MALDI-TOF mass spectral analysis of siRNA degradation in serum confirms an RNAse A-like activity

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

RNA Interference with chemically modified siRNA.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Characterization of the ribonuclease activity on the skin surface

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

RNAi: a novel antisense technology and its therapeutic potential

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Progress towards in vivo use of siRNAs

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

The genetic basis of pachyonychia congenita.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Functional polarity is introduced by Dicer processing of short substrate RNAs

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

In vivo activity of nuclease-resistant siRNAs

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

RNAse A-like enzymes in serum inhibit the anti-neoplastic activity of siRNA targeting polo-like kinase 1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Inhibition of RNAse A family enzymes prevents degradation and loss of silencing activity of siRNAs in serum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

siRNA function in RNAi: a chemical modification analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Inhibition of respiratory viruses by nasally administered siRNA.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

RNA interference in mammalian cells by chemically-modified RNA.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829675

RNA interference targeting Fas protects mice from fulminant hepatitis

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18844576

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18844576

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/OLI.2008.0149

1 reference

release_eaq3dub63bai7d22q6trepixd4

11 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eaq3dub63bai7d22q6trepixd4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

11 September 2017

PubMed publication ID

18844576

1 reference