Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis (Q39326566)

11 September 2017

Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis (English)

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11 September 2017

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7

Stuart L Schreiber

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11 September 2017

Danny Hung-Chieh Chou

1

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11 September 2017

Edward B Holson

2

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11 September 2017

Florence F Wagner

3

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11 September 2017

Alicia J Tang

4

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11 September 2017

Rebecca L Maglathlin

5

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11 September 2017

Timothy A Lewis

6

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11 September 2017

Bridget K Wagner

8

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11 September 2017

1 June 2012

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11 September 2017

Chemistry and Biology

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19

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6

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11 September 2017

669-673

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Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Chemical phylogenetics of histone deacetylases

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Comparison of in vitro assays of cellular toxicity in the human hepatic cell line HepG2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Mitochondrial membrane potential monitored by JC-1 dye.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383610

Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22726680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22726680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytotoxic effect of IFN-gamma plus TNF-alpha on human islet cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22726680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHEMBIOL.2012.05.010

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11 September 2017

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11 September 2017

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