MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells (Q39329640)

11 September 2017

title

MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells (English)

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11 September 2017

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Borhane Annabi

1

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11 September 2017

Eric Vaillancourt-Jean

series ordinal

2

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11 September 2017

Richard Béliveau

series ordinal

3

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11 September 2017

publication date

16 June 2012

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11 September 2017

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11 September 2017

volume

21

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11 September 2017

issue

1

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11 September 2017

page(s)

91-99

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PGE2 induces angiogenesis via MT1-MMP-mediated activation of the TGFbeta/Alk5 signaling pathway.

11 September 2017

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Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype.

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The diet-derived sulforaphane inhibits matrix metalloproteinase-9-activated human brain microvascular endothelial cell migration and tubulogenesis.

21 January 2018

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Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling

21 January 2018

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A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells

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Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion

21 January 2018

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Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells

21 January 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

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Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision

21 January 2018

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Changing views of the role of matrix metalloproteinases in metastasis

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MT1-MMP down-regulates the glucose 6-phosphate transporter expression in marrow stromal cells: a molecular link between pro-MMP-2 activation, chemotaxis, and cell survival.

21 January 2018

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Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

21 January 2018

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New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.

21 January 2018

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Silencing of the MT1-MMP/ G6PT axis suppresses calcium mobilization by sphingosine-1-phosphate in glioblastoma cells

21 January 2018

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Tetra- and hexavalent mannosides inhibit the pro-apoptotic, antiproliferative and cell surface clustering effects of concanavalin-A: impact on MT1-MMP functions in marrow-derived mesenchymal stromal cells

21 January 2018

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NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis.

21 January 2018

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21 January 2018

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A role for MT1-MMP as a cell death sensor/effector through the regulation of endoplasmic reticulum stress in U87 glioblastoma cells

21 January 2018

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Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene.

21 January 2018

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Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.

21 January 2018

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Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.

21 January 2018

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Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and metastasis

21 January 2018

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Beneficial health effects of lupeol triterpene: a review of preclinical studies

21 January 2018

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The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKgamma/NF-kappaB-dependent pathway

21 January 2018

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21 January 2018

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Role of lupeol and lupeol linoleate on lipemic-oxidative stress in experimental hypercholesterolemia

21 January 2018

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Membrane type 1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-related kinase activation and cell migration

21 January 2018

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Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol

21 January 2018

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COX inhibitors directly alter gene expression: role in cancer prevention?

21 January 2018

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Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils

21 January 2018

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TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP.

21 January 2018

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12 December 2020

Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells

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12 December 2020

Protective effect of lupeol and its ester on cardiac abnormalities in experimental hypercholesterolemia

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12 December 2020

Role of nutrition in preventing cancer

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12 December 2020

Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats

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12 December 2020

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer

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12 December 2020

Low intracellular ATP levels exacerbate carcinogen-induced inflammatory stress response and inhibit in vitro tubulogenesis in human brain endothelial cells

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12 December 2020

Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.

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12 December 2020

Sinomenine reduces invasion and migration ability in fibroblast-like synoviocytes cells co-cultured with activated human monocytic THP-1 cells by inhibiting the expression of MMP-2, MMP-9, CD147

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12 December 2020

Glioblastoma multiforme: a review of therapeutic targets

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12 December 2020

Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma

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12 December 2020

Craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma

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12 December 2020

Matrix metalloproteinases involvement in pathologic conditions

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12 December 2020

Radiation induced-tubulogenesis in endothelial cells is antagonized by the antiangiogenic properties of green tea polyphenol (-) epigallocatechin-3-gallate

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12 December 2020

10.1007/S10787-012-0142-8

Identifiers

DOI

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11 September 2017

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