Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage (Q39342682)

11 September 2017

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage (English)

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11 September 2017

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10

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11 September 2017

Marzia Pennati

4

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Marco Folini

Marco Folini

9

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Federica Perrone

Federica Perrone

6

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Manlio Palumbo

Manlio Palumbo

7

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Maria Grazia Daidone

Maria Grazia Daidone

8

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author name string

Nicola Ivan Orlotti

1

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11 September 2017

Graziella Cimino-Reale

2

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11 September 2017

Erika Borghini

3

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11 September 2017

Claudia Sissi

5

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11 September 2017

25 May 2012

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11 September 2017

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11 September 2017

8

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11 September 2017

8

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11 September 2017

1185-1196

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Hallmarks of Cancer: The Next Generation

11 September 2017

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https://api.crossref.org/works/10.4161%2FAUTO.20519

Telomeres as targets for anticancer therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

How telomeres solve the end-protection problem

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Human telomeric G-quadruplex: the current status of telomeric G-quadruplexes as therapeutic targets in human cancer

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.20519

Quadruplex DNA crystal structures and drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

A G-quadruplex stabilizer induces M-phase cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Methods in mammalian autophagy research

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Stage-specific effect of inhibition of autophagy on chemotherapy-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Autophagy: an emerging target for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Chemical modulators of autophagy as biological probes and potential therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

A new era: melanoma genetics and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Weak p53 permits senescence during cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

TP53 and MTOR crosstalk to regulate cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Inhibition of MEK/ERK signaling synergistically potentiates histone deacetylase inhibitor-induced growth arrest, apoptosis and acetylation of histone H3 on p21waf1 promoter in acute myelogenous leukemia cell

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Autophagy: Molecular mechanisms and their implications for anticancer therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Autophagy modulation for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Autophagy in cutaneous malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Control of autophagy by oncogenes and tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.20519

21 January 2018

Identifiers

DOI

10.4161/AUTO.20519

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11 September 2017

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