The Role of PIEZO2 in Human Mechanosensation (Q39366628)

http://europepmc.org/abstract/PMC/5911918

14 June 2018

title

The Role of PIEZO2 in Human Mechanosensation. (English)

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http://europepmc.org/abstract/PMC/5911918

14 June 2018

1 reference

1

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1 June 2020

Carla M Grosmann

13

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11

A Micheil Innes

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1 June 2020

2

Marcin Szczot

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1 June 2020

author name string

Diana Bharucha-Goebel

3

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1 June 2020

Marta Čeko

4

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1 June 2020

Sandra Donkervoort

5

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1 June 2020

Claire Laubacher

6

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1 June 2020

Leslie H Hayes

7

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1 June 2020

Katharine Alter

8

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1 June 2020

Cristiane Zampieri

9

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1 June 2020

Christopher Stanley

10

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1 June 2020

Jean K Mah

12

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1 June 2020

Nathaniel Bradley

14

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1 June 2020

David Nguyen

15

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1 June 2020

A Reghan Foley

16

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1 June 2020

Claire E Le Pichon

17

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1 June 2020

Carsten G Bönnemann

18

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1 June 2020

language of work or name

English

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publication date

21 September 2016

1 reference

http://europepmc.org/abstract/PMC/5911918

14 June 2018

published in

The New England Journal of Medicine

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1 June 2020

volume

375

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1 June 2020

issue

14

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1 June 2020

page(s)

1355-1364

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Feeling force: physical and physiological principles enabling sensory mechanotransduction

1 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Piezo2 is the principal mechanotransduction channel for proprioception.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Architecture of the mammalian mechanosensitive Piezo1 channel

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Mammalian touch catches up

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Piezo1 ion channel pore properties are dictated by C-terminal region.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Internal and External Feedback Circuits for Skilled Forelimb Movement

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Whole-body mapping of spatial acuity for pain and touch

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

The functional and anatomical dissection of somatosensory subpopulations using mouse genetics

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Presynaptic inhibition of spinal sensory feedback ensures smooth movement

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Merkel cells transduce and encode tactile stimuli to drive Aβ-afferent impulses

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Mutations in PIEZO2 cause Gordon syndrome, Marden-Walker syndrome, and distal arthrogryposis type 5.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Piezo2 is required for Merkel-cell mechanotransduction

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

α1F64 Residue at GABA(A) receptor binding site is involved in gating by influencing the receptor flipping transitions.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

The sensory neurons of touch

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

A genetic basis for mechanosensory traits in humans

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Exome sequencing identifies the cause of a mendelian disorder

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Somatotopic organization of gentle touch processing in the posterior insular cortex

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

An SCN9A channelopathy causes congenital inability to experience pain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Erythromelalgia: a hereditary pain syndrome enters the molecular era.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Nonsense-mediated mRNA decay: terminating erroneous gene expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Unmyelinated tactile afferents signal touch and project to insular cortex.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

Brain mechanisms for processing affective touch.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911918

21 August 2018

Identifiers

DOI

10.1056/NEJMOA1602812

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27653382%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27653382%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

27653382

1 reference