Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells (Q39384352)

11 September 2017

Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells (English)

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11 September 2017

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chronic myeloid leukemia

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Y Yu

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11 September 2017

L Yang

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M Zhao

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S Zhu

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R Kang

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P Vernon

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D Tang

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L Cao

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7 March 2012

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26

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8

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1752-1760

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https://scigraph.springernature.com/pub.10.1038/leu.2012.65

11 September 2017

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Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells

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MicroRNAs: genomics, biogenesis, mechanism, and function

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The role of microRNA in human leukemia: a review

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MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations

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microRNA-101 is a potent inhibitor of autophagy

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MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy

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Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.

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HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells

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Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein

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Lithium induces autophagy by inhibiting inositol monophosphatase

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ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia

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Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

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Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease.

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The anticancer drug imatinib induces cellular autophagy.

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Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

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MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

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Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

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miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway

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Autophagy regulation by p53.

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TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes

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Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional regulatory regions of the gene

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7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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7 January 2021

The Beclin 1 network regulates autophagy and apoptosis

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A protein conjugation system essential for autophagy

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

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Movement of Bax from the cytosol to mitochondria during apoptosis

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Bax directly induces release of cytochrome c from isolated mitochondria

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The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

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Chapter 10 Monitoring Autophagy by Electron Microscopy in Mammalian Cells

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7 January 2021

Identifiers

DOI

10.1038/LEU.2012.65

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release_4l3lla2hhzfork7fjxk5kc5jx4

11 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/4l3lla2hhzfork7fjxk5kc5jx4

24 November 2022

mapped directly with Wikidata item

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