JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells (Q39384513)

11 September 2017

title

JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells (English)

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11 September 2017

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Zhiwei Zhao

1

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11 September 2017

Jingjing Wang

2

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11 September 2017

Jingsheng Tang

3

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11 September 2017

Xinyu Liu

4

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11 September 2017

Qian Zhong

5

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11 September 2017

Fang Wang

6

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11 September 2017

Wenbin Hu

7

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11 September 2017

Zhu Yuan

8

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11 September 2017

Chunlai Nie

9

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11 September 2017

Yuquan Wei

10

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11 September 2017

language of work or name

English

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publication date

1 June 2012

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11 September 2017

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11 September 2017

volume

444

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11 September 2017

issue

2

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11 September 2017

page(s)

291-301

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11 September 2017

cites work

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SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events

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Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function

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Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101.

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BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells

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Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells.

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

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PUMA, a novel proapoptotic gene, is induced by p53

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Downregulation of XIAP expression in ovarian cancer cells induces cell death in vitro and in vivo.

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Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

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Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

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21 January 2018

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Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite

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Bim protein degradation contributes to cisplatin resistance

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21 January 2018

Identifiers

DOI

10.1042/BJ20111855

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11 September 2017

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