Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1). (Q39396524)

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23 January 2020

title

Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1) (English)

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23 January 2020

3

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23 January 2020

author name string

Chen Feng

1

1 reference

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23 January 2020

Yan-Feng Li

2

1 reference

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23 January 2020

Hui-Shan Lee

4

1 reference

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23 January 2020

Xiao-Yan Tang

5

1 reference

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23 January 2020

Zhi-Hong Xue

6

1 reference

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23 January 2020

Yi-Chao Zhou

7

1 reference

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23 January 2020

Wei-Min Lim

8

1 reference

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23 January 2020

Tobias C Cornvik

9

1 reference

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23 January 2020

Christiane Ruedl

10

1 reference

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23 January 2020

Susana G Shochat

11

1 reference

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23 January 2020

Suet-Mien Tan

12

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23 January 2020

language of work or name

English

0 references

publication date

10 February 2012

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Journal of Biological Chemistry

23 January 2020

published in

1 reference

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23 January 2020

volume

287

1 reference

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23 January 2020

issue

14

1 reference

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23 January 2020

page(s)

10714-10726

1 reference

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Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils

23 January 2020

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The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell

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The final steps of integrin activation: the end game

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New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering

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The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

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The Kindlin protein family: new members to the club of focal adhesion proteins

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Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes

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Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

11 September 2017

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The tail of integrins, talin, and kindlins

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The ins and outs of leukocyte integrin signaling

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Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects

11 September 2017

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Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation

11 September 2017

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Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells

11 September 2017

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A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans

11 September 2017

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Integrins and cell-fate determination

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Migfilin, a molecular switch in regulation of integrin activation

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Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunits

11 September 2017

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RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma

11 September 2017

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Kindlin-2 controls bidirectional signaling of integrins

11 September 2017

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Kindlin-3 is essential for integrin activation and platelet aggregation

11 September 2017

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Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration

11 September 2017

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Structure and mechanics of integrin-based cell adhesion.

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RACK1 regulates Src activity and modulates paxillin dynamics during cell migration

11 September 2017

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Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.

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Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

11 September 2017

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RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site

11 September 2017

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11 September 2017

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Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

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11 September 2017

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11 September 2017

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Mediation of Rac1 activation by kindlin-2: an essential function in osteoblast adhesion, spreading, and proliferation

11 September 2017

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Role of kindlin-2 in fibroblast functions: implications for wound healing.

11 September 2017

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14 September 2017

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Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

14 September 2017

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14 September 2017

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The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

14 September 2017

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Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta

14 September 2017

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14 September 2017

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14 September 2017

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15 June 2018

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Anchoring proteins for protein kinase C: a means for isozyme selectivity

15 June 2018

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Kindlin-2: a novel adhesion protein related to tumor invasion, lymph node metastasis, and patient outcome in gastric cancer.

15 June 2018

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21 August 2018

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SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function

21 August 2018

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21 August 2018

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 August 2018

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Defining the repeating elements in the cysteine-rich region (CRR) of the CD18 integrin beta 2 subunit

21 August 2018

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The WD protein Rack1 mediates protein kinase C and integrin-dependent cell migration.

21 August 2018

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The Coatomer Protein '-COP, a Selective Binding Protein (RACK) for Protein Kinase C

21 August 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.299594

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)

21 January 2018

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Improving biosensor analysis

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22334666

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A human lymphocyte-associated antigen involved in cell-mediated lympholysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22334666

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.299594

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22334666%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22334666%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

22334666

1 reference