Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides (Q40606401)

22 September 2017

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides (English)

1 reference

22 September 2017

Bing-Hao Luo

1

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22 September 2017

Junichi Takagi

series ordinal

2

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22 September 2017

Timothy A Springer

series ordinal

3

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22 September 2017

language of work or name

English

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publication date

16 December 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

279

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22 September 2017

11

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22 September 2017

10215-10221

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Integrins: bidirectional, allosteric signaling machines

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Conformational regulation of integrin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Structure of integrin alpha5beta1 in complex with fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Structural basis of collagen recognition by integrin alpha2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Accurate modeling of protein conformation by automatic segment matching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Folding of the beta-propeller domain of the integrin alphaL subunit is independent of the I domain and dependent on the beta2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

A redox site involved in integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

New isolation procedure and further biochemical characterization of glycoproteins IIb and IIIa from human platelet plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

Thiol-specific probes indicate that the beta-chain of platelet glycoprotein Ib is a transmembrane protein with a reactive endofacial sulfhydryl group

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312732200

21 January 2018

Identifiers

DOI

10.1074/JBC.M312732200

1 reference

22 September 2017

1 reference