miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. (Q39411578)

11 September 2017

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. (English)

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11 September 2017

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4

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11 September 2017

Gozde Korkmaz

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Kumsal Ayse Tekirdag

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Kumsal Ayse Tekirdag

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3

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Devrim Gözüaçık

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Devrim Gozuacik

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5

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author name string

Carlos le Sage

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11 September 2017

1 February 2012

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11 September 2017

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11 September 2017

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11 September 2017

2

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11 September 2017

165-176

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Autophagy: process and function

11 September 2017

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

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Autophagy fights disease through cellular self-digestion

21 January 2018

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Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Autophagy as a cell death and tumor suppressor mechanism

21 January 2018

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Regulation mechanisms and signaling pathways of autophagy

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Overview of macroautophagy regulation in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

The autophagy effector Beclin 1: a novel BH3-only protein

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Regulation of membrane biogenesis in autophagy via PI3P dynamics

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Two ubiquitin-like conjugation systems essential for autophagy

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

A ubiquitin-like system mediates protein lipidation

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Role of the Apg12 conjugation system in mammalian autophagy

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

21 January 2018

1 reference

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Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

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Selective autophagy mediated by autophagic adapter proteins

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

The functions of animal microRNAs

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Immense promises for tiny molecules: uncovering miRNA functions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

21 January 2018

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A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Structural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Microarray profiling of microRNAs expressed in testis tissues of developing primates.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Redirection of silencing targets by adenosine-to-inosine editing of miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Small RNA expression and strain specificity in the rat

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

The microRNA spectrum in 12 body fluids

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

MicroRNA targets in Drosophila

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Patterns of microRNA expression in non-human primate cells correlate with neoplastic development in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

21 January 2018

1 reference

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Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Role of autophagy in suppression of inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Autophagy in disease: a double-edged sword with therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Chemical modulators of autophagy as biological probes and potential therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Targeting miRNAs for drug discovery: a new paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Dynamics of RASSF1A/MOAP-1 association with death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.8.2.18351

21 January 2018

Identifiers

DOI

10.4161/AUTO.8.2.18351

1 reference

11 September 2017

1 reference

PubMed ID

22248718