Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation (Q39425996)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179839%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation (English)

1 reference

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18 January 2020

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2

1 reference

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18 January 2020

Corrado Santocanale

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179839%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Lawrence Gardner

series ordinal

4

1 reference

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18 January 2020

author name string

L Martin

series ordinal

1

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

19 December 2011

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18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179839%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

31

1 reference

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18 January 2020

issue

36

1 reference

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18 January 2020

page(s)

4076-4084

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2011.585

18 January 2020

exact match

0 references

cites work

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Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage

11 September 2017

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APC/C--the master controller of origin licensing?

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CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

11 September 2017

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Involvement of the SCF complex in the control of Cdh1 degradation in S-phase

11 September 2017

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The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation

11 September 2017

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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

11 September 2017

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

11 September 2017

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Replication protein A (RPA) phosphorylation prevents RPA association with replication centers

11 September 2017

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Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

11 September 2017

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

11 September 2017

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

11 September 2017

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An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

11 September 2017

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An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

11 September 2017

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Hypoxia links ATR and p53 through replication arrest

11 September 2017

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11 September 2017

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11 September 2017

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

11 September 2017

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11 September 2017

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ATR disruption leads to chromosomal fragmentation and early embryonic lethality

11 September 2017

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

11 September 2017

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11 September 2017

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CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

11 September 2017

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Cdc6 protein causes premature entry into S phase in a mammalian cell-free system

11 September 2017

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Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

11 September 2017

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

11 September 2017

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11 September 2017

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11 September 2017

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11 September 2017

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14 September 2017

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Hypoxic suppression of the cell cycle gene CDC25A in tumor cells

14 September 2017

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Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation

14 September 2017

1 reference

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Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a

14 September 2017

1 reference

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ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation

14 September 2017

1 reference

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Tumor hypoxia and the cell cycle: implications for malignant progression and response to therapy

14 September 2017

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Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21.

17 June 2018

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Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest

21 August 2018

1 reference

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The range of oxygenation in SiHa tumor xenografts

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310967

Hypoxia inhibits G1/S transition through regulation of p27 expression

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2011.585

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22179839

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.585

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179839%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179839%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference