Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer (Q39430345)

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English	Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer	scientific article

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scholarly article

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Europe PubMed Central

11 September 2017

Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer (English)

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Europe PubMed Central

11 September 2017

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C Alberti

1

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Europe PubMed Central

11 September 2017

P Pinciroli

2

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Europe PubMed Central

11 September 2017

B Valeri

3

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Europe PubMed Central

11 September 2017

R Ferri

4

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Europe PubMed Central

11 September 2017

A Ditto

5

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Europe PubMed Central

11 September 2017

K Umezawa

6

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Europe PubMed Central

11 September 2017

M Sensi

7

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Europe PubMed Central

11 September 2017

S Canevari

8

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Europe PubMed Central

11 September 2017

A Tomassetti

9

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11 September 2017

language of work or name

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publication date

12 December 2011

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11 September 2017

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Europe PubMed Central

11 September 2017

31

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11 September 2017

37

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11 September 2017

4139-4149

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Europe PubMed Central

11 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2011.572

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Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.

1 reference

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The biology of ovarian cancer: new opportunities for translation

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Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

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Lysophosphatidic acid, a disintegrin and metalloprotease-17 and heparin-binding epidermal growth factor-like growth factor in ovarian cancer: the first word, not the last

1 reference

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21 January 2018

Functional proteomic analysis of advanced serous ovarian cancer using reverse phase protein array: TGF-beta pathway signaling indicates response to primary chemotherapy

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https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.

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https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Role of the epidermal growth factor network in ovarian follicles.

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Evolving role of uPA/uPAR system in human cancers

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E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells

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Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas

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21 January 2018

Integrated genomic analyses of ovarian carcinoma

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Effects of siltuximab on the IL-6-induced signaling pathway in ovarian cancer

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21 January 2018

Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype

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21 January 2018

Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.

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21 January 2018

HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis

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https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Activated epidermal growth factor receptor in ovarian cancer.

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https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

CARMA3 is crucial for EGFR-Induced activation of NF-κB and tumor progression

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https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Nuclear factor-kappaB in cancer development and progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

IL-6 production in ovarian carcinoma is associated with histiotype and biological characteristics of the tumour and influences local immunity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Cell signaling by receptor tyrosine kinases

1 reference

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EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCdelta, and sphingosine kinase 1 in glioblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.

1 reference

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Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression

1 reference

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21 January 2018

Variant HNF1 modulates epithelial plasticity of normal and transformed ovary cells.

1 reference

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Anti-tumor efficacy of an anti-epidermal-growth-factor-receptor monoclonal antibody and its F(ab')2 fragment against high- and low-EGFR-expressing carcinomas in nude mice

1 reference

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21 January 2018

Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

1 reference

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Inhibition of tumor growth by NF-kappaB inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

21 January 2018

NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation

1 reference

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21 January 2018

Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues

1 reference

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21 January 2018

New potential ligand-receptor signaling loops in ovarian cancer identified in multiple gene expression studies

1 reference

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31 March 2020

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.572

31 March 2020

Cytokines IL-1beta, IL-2, IL-6, IL-8, MCP-1, GM-CSF and TNFalpha in patients with epithelial ovarian cancer and their relationship to treatment with paclitaxel

1 reference

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31 March 2020

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10.1038/ONC.2011.572

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Europe PubMed Central

11 September 2017

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1 reference

Europe PubMed Central

11 September 2017

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