Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac. (Q39430718)

11 September 2017

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac. (English)

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11 September 2017

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Katrin Deinhardt

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Elizabeth A. Eipper

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Betty A Eipper

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Richard E Mains

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Taeho Kim

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Daniel S Spellman

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Thomas A Neubert

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Barbara L Hempstead

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ra82

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describes a project that uses

11 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3360552/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio

1 reference

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Migrastatin analogues target fascin to block tumour metastasis

11 September 2017

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Neurotrophin receptors: Old friends with new partners

11 September 2017

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Brain-derived neurotrophic factor and the development of structural neuronal connectivity

11 September 2017

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Molecular and Structural Insight into proNGF Engagement of p75NTR and Sortilin

11 September 2017

1 reference

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Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease

11 September 2017

1 reference

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NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death

11 September 2017

1 reference

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Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

11 September 2017

1 reference

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Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures

11 September 2017

1 reference

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Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy

11 September 2017

1 reference

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Lifeact: a versatile marker to visualize F-actin

11 September 2017

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Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

11 September 2017

1 reference

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Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation

11 September 2017

1 reference

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Axon pruning in the developing vertebrate hippocampus

11 September 2017

1 reference

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Role of fascin in filopodial protrusion

11 September 2017

1 reference

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Axon retraction and degeneration in development and disease

11 September 2017

1 reference

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Multiple novel isoforms of Trio are expressed in the developing rat brain

11 September 2017

1 reference

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Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

11 September 2017

1 reference

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Sortilin is essential for proNGF-induced neuronal cell death

11 September 2017

1 reference

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Curbing the excesses of youth: molecular insights into axonal pruning.

11 September 2017

1 reference

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Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

11 September 2017

1 reference

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The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth

11 September 2017

1 reference

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Regulation of cell survival by secreted proneurotrophins

11 September 2017

1 reference

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Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

11 September 2017

1 reference

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Role of the actin bundling protein fascin in growth cone morphogenesis: localization in filopodia and lamellipodia

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPases

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth

11 September 2017

1 reference

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Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

Two conserved domains in the NGF propeptide are necessary and sufficient for the biosynthesis of correctly processed and biologically active NGF.

11 September 2017

1 reference

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Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio

11 September 2017

1 reference

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A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway

14 September 2017

1 reference

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Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.

14 September 2017

1 reference

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ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

14 September 2017

1 reference

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Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

14 September 2017

1 reference

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Neurotrophins regulate dendritic growth in developing visual cortex

25 September 2017

1 reference

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MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

Mesenchymal and neuronal cell expression of the p75 neurotrophin receptor gene occur by different mechanisms

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360552

Analysis of G-protein-coupled receptor dimerization following chemokine signaling

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002060

Filopodial behavior is dependent on the phosphorylation state of neuronal growth cones

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22155786

12 December 2020

inferred from PubMed ID database lookup

p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22155786

12 December 2020

inferred from PubMed ID database lookup

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22155786

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCISIGNAL.2002060

1 reference

11 September 2017

1 reference

11 September 2017

1 reference