A framework for understanding the roles of miRNAs in animal development (Q39442714)

12 September 2017

A framework for understanding the roles of miRNAs in animal development (English)

1 reference

12 September 2017

2

Luisa Cochella

1 reference

12 September 2017

Chiara Alberti

1

1 reference

PubMed ID

28720652

12 September 2017

language of work or name

English

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publication date

1 July 2017

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12 September 2017

12

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based on heuristic

inferred from page(s)

published in

Development

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12 September 2017

144

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12 September 2017

2548-2559

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12 September 2017

14

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The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans

12 September 2017

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Many families of C. elegans microRNAs are not essential for development or viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The functions of animal microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Diversifying microRNA sequence and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs in the Drosophila bithorax complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Dicer is essential for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

bantam miRNA promotes systemic growth by connecting insulin signaling and ecdysone production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The evolution of gene regulation by transcription factors and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Systematic study of Drosophila microRNA functions using a collection of targeted knockout mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Canonical and alternate functions of the microRNA biogenesis machinery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Embryonic priming of a miRNA locus predetermines postmitotic neuronal left/right asymmetry in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Diverse functions of microRNAs in nervous system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Denoising feedback loops by thresholding--a new role for microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Gene regulatory networks and the evolution of animal body plans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Regulatory gene networks and the properties of the developmental process

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Neuron type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The let-7 microRNA directs vulval development through a single target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A genome-wide survey of sexually dimorphic expression of Drosophila miRNAs identifies the steroid hormone-induced miRNA let-7 as a regulator of sexual identity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Regulation of Maternal mRNAs in Early Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Zebrafish organizer development and germ-layer formation require nodal-related signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Co-activation of microRNAs by Zelda is essential for early Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Homeotic function of Drosophila Bithorax-complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs regulate brain morphogenesis in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Drosha regulates gene expression independently of RNA cleavage function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Regulation of microRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

microRNA control of cell-cell signaling during development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Spatial expression of transcription factors in Drosophila embryonic organ development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Gene regulation by transcription factors and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Development of left/right asymmetry in the Caenorhabditis elegans nervous system: from zygote to postmitotic neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Terminal Selectors of Neuronal Identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The Functions of MicroRNAs: mRNA Decay and Translational Repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Essential role for Argonaute2 protein in mouse oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The microRNA miR-8 is a conserved negative regulator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A single female-specific piRNA is the primary determiner of sex in the silkworm

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Maternal loss of miRNAs leads to increased variance in primordial germ cell numbers in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A mammalian microRNA expression atlas based on small RNA library sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A microRNA imparts robustness against environmental fluctuation during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MiR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs as components of systemic signaling pathways in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Deadenylation of maternal mRNAs mediated by miR-427 in Xenopus laevis embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

DGCR8 HITS-CLIP reveals novel functions for the Microprocessor

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Promotion of embryonic cortico-cerebral neuronogenesis by miR-124.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A Drosophila pasha mutant distinguishes the canonical microRNA and mirtron pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The embryonic mir-35 family of microRNAs promotes multiple aspects of fecundity in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A microRNA family exerts maternal control on sex determination in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Let's make it happen: the role of let-7 microRNA in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Critical roles for Dicer in the female germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

egl-1: a key activator of apoptotic cell death in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The miR-310/13 cluster antagonizes β-catenin function in the regulation of germ and somatic cell differentiation in the Drosophila testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs involved in bone formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Two miRNA clusters reveal alternative paths in late-stage reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A resource for the conditional ablation of microRNAs in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Evolution of gene regulatory networks controlling body plan development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNAs and their roles in developmental canalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

A variety of dicer substrates in human and C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The conserved miR-51 microRNA family is redundantly required for embryonic development and pharynx attachment in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miRNAs cooperate in apoptosis regulation during C. elegans development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA, and siRNA pathways in nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Functional screening identifies miR-315 as a potent activator of Wingless signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Pervasive roles of microRNAs in cardiovascular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The role of microRNAs in muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Identification of Drosophila MicroRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA function is globally suppressed in mouse oocytes and early embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The embryonic cell lineage of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Multiple In Vivo Biological Processes Are Mediated by Functionally Redundant Activities of Drosophila mir-279 and mir-996.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-430 regulates oriented cell division during neural tube development in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Maternal microRNAs are essential for mouse zygotic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Post-transcriptional control of DGCR8 expression by the Microprocessor

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The microRNA-producing enzyme Dicer1 is essential for zebrafish development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA expression in zebrafish embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Systematic characterization of small RNAome during zebrafish early developmental stages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

MicroRNA-mediated conversion of human fibroblasts to neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FDEV.146613

21 January 2018

Identifiers

DOI

10.1242/DEV.146613

1 reference

12 September 2017

1 reference

PubMed ID

28720652