Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation. (Q39446908)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454535%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation (English)

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11 December 2019

5

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11 December 2019

author name string

L A Cass

1

1 reference

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11 December 2019

S A Summers

2

1 reference

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11 December 2019

G V Prendergast

3

1 reference

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11 December 2019

J M Backer

4

1 reference

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11 December 2019

J L Meinkoth

6

1 reference

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11 December 2019

language of work or name

English

0 references

publication date

1 September 1999

1 reference

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Molecular and Cellular Biology

11 December 2019

published in

1 reference

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11 December 2019

volume

19

1 reference

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11 December 2019

issue

9

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11 December 2019

page(s)

5882-5891

1 reference

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A family of cAMP-binding proteins that directly activate Rap1

11 December 2019

cites work

1 reference

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

12 September 2017

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A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

12 September 2017

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Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

12 September 2017

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

12 September 2017

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Signaling through scaffold, anchoring, and adaptor proteins

12 September 2017

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Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells

12 September 2017

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Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

12 September 2017

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Phosphoinositide 3-kinases: a conserved family of signal transducers

12 September 2017

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The modular phosphorylation and activation of p70s6k.

12 September 2017

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

12 September 2017

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The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor

12 September 2017

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RalGDS functions in Ras- and cAMP-mediated growth stimulation

12 September 2017

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Mechanism of activation of protein kinase B by insulin and IGF-1

12 September 2017

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Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

12 September 2017

1 reference

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

12 September 2017

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Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase

12 September 2017

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

12 September 2017

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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

12 September 2017

1 reference

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Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression

12 September 2017

1 reference

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Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

12 September 2017

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A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

12 September 2017

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

12 September 2017

1 reference

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

12 September 2017

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

12 September 2017

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Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

12 September 2017

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

12 September 2017

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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

12 September 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

12 September 2017

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

12 September 2017

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

12 September 2017

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Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

12 September 2017

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Differential effects of protein kinase A on Ras effector pathways

12 September 2017

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Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.

14 September 2017

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Regulation of Ras-mediated signalling: more than one way to skin a cat.

14 September 2017

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Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

14 September 2017

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Multiple facets of the modulation of growth by cAMP.

14 September 2017

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G-protein coupled receptor-mediated activation of PI 3-kinase in neutrophils

14 September 2017

1 reference

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Differential effects of cyclic adenosine 3',5'-monophosphate on p70 ribosomal S6 kinase

25 September 2017

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The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

25 September 2017

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Rac1 is required for cell proliferation and G2/M progression.

25 September 2017

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Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells

25 September 2017

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Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

25 September 2017

1 reference

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Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

25 September 2017

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Ras inhibits thyroglobulin expression but not cyclic adenosine monophosphate-mediated signaling in Wistar rat thyrocytes

25 September 2017

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Activation of p70/p85 S6 kinase by a pathway independent of p21ras

25 September 2017

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Differentiation-dependent suppression of platelet-derived growth factor signaling in cultured adipocytes

25 September 2017

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A Rac1 effector site controlling mitogenesis through superoxide production

17 June 2018

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Mechanism of activation and function of protein kinase B.

17 June 2018

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Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

17 June 2018

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PDK1, one of the missing links in insulin signal transduction?

17 June 2018

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The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

17 June 2018

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CD31-triggered rearrangement of the actin cytoskeleton in human natural killer cells.

17 June 2018

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A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol

17 June 2018

1 reference

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Cyclic AMP-dependent activation of Rap1b

17 June 2018

1 reference

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An essential role for Rac in Ras transformation

17 June 2018

1 reference

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Dissociation of cAMP-stimulated Mitogenesis from Activation of the Mitogen-activated Protein Kinase Cascade in Swiss 3T3 Cells

17 June 2018

1 reference

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Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

17 June 2018

1 reference

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Synergistic stimulation of DNA synthesis by cyclic AMP derivatives and growth factors in mouse 3T3 cells

17 June 2018

1 reference

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

17 June 2018

1 reference

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Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs

17 June 2018

1 reference

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

17 June 2018

1 reference

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A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells

21 August 2018

1 reference

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A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils

21 August 2018

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Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases

21 August 2018

1 reference

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Mechanism of inhibition of Raf-1 by protein kinase A.

21 August 2018

1 reference

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Suppression of insulin-stimulated phosphatidylinositol 3-kinase activity by the beta3-adrenoceptor agonist CL316243 in rat adipocytes

21 August 2018

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12 December 2020

Lipid-Regulated Kinases: Some Common Themes at Last

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12 December 2020

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

1 reference

12 December 2020

cAMP stimulates protein kinase B in a Wortmannin-insensitive manner

1 reference

12 December 2020

Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway

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12 December 2020

Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex

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12 December 2020

Class II cytoplasmic and transmembrane domains are not required for class II-mediated B cell spreading

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12 December 2020

Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx

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12 December 2020

Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation

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12 December 2020

Identifiers

DOI

10.1128/MCB.19.9.5882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454535%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454535%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

PubMed publication ID

10454535

1 reference