Modulation of AKT activity is associated with reversible dormancy in ascites-derived epithelial ovarian cancer spheroids (Q39449455)

12 September 2017

title

Modulation of AKT activity is associated with reversible dormancy in ascites-derived epithelial ovarian cancer spheroids (English)

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12 September 2017

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Rohann J M Correa

1

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12 September 2017

Teresa Peart

2

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12 September 2017

Yudith Ramos Valdes

3

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12 September 2017

Gabriel E DiMattia

4

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12 September 2017

Trevor G Shepherd

5

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12 September 2017

language of work or name

English

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publication date

31 October 2011

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12 September 2017

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12 September 2017

volume

33

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12 September 2017

issue

1

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12 September 2017

page(s)

49-58

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

12 September 2017

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The biology of ovarian cancer: new opportunities for translation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Multicellular spheroids in ovarian cancer metastases: Biology and pathology.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Pathogenesis of malignant ascites: Starling's law of capillary hemodynamics revisited

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/Rb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Disaggregation and invasion of ovarian carcinoma ascites spheroids

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Effect of the cyclin-dependent kinases inhibitor p27 on resistance of ovarian cancer multicellular spheroids to anticancer chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

PI3K/Akt: getting it right matters

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Frequent mutation of the PIK3CA gene in ovarian and breast cancers

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

PIK3CA mutations in advanced ovarian carcinomas

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Ovarian cancer spheroids use myosin-generated force to clear the mesothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Identification and characterization of ovarian cancer-initiating cells from primary human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

BMP4 induces EMT and Rho GTPase activation in human ovarian cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

The prognostic significance of elongation factor eEF1A2 in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

AKT/PKB signaling: navigating downstream

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Malignant pleural mesothelioma cells resist anoikis as quiescent pluricellular aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

CD44 and beta1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Ovarian cancer pathogenesis: a model in evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR241

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGR241

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12 September 2017

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