1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation (Q39465525)

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scientific article published on 29 September 2011

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English	1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation	scientific article published on 29 September 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 September 2017

1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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1 reference

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author name string

Teng Yu

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Jinchao Li

2

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Europe PubMed Central

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12 September 2017

Ying Qiu

3

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12 September 2017

Hui Sun

4

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Europe PubMed Central

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12 September 2017

publication date

29 September 2011

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Europe PubMed Central

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12 September 2017

Molecular and Cellular Biochemistry

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12 September 2017

361

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Europe PubMed Central

PubMed publication ID

12 September 2017

1-2

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Europe PubMed Central

PubMed publication ID

12 September 2017

47-54

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Europe PubMed Central

PubMed publication ID

12 September 2017

Apoptosis and melanoma chemoresistance

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Adjuvant therapy of malignant melanoma

1 reference

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21 January 2018

Curcumin as "Curecumin": from kitchen to clinic.

1 reference

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21 January 2018

Curcumin: the story so far.

1 reference

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Phase II trial of curcumin in patients with advanced pancreatic cancer

1 reference

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Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Biologically active sphingolipids in cancer pathogenesis and treatment

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Glucosylceramide synthase and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: more than just AKT inhibition

1 reference

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Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells

1 reference

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The Akt-mTOR tango and its relevance to cancer

1 reference

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21 January 2018

Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Survivin Enhances Motility of Melanoma Cells by Supporting Akt Activation and α5 Integrin Upregulation

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Signal transduction of stress via ceramide

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Metabolism and apoptotic properties of elevated ceramide in HT29rev cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1 reference

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21 January 2018

Paclitaxel-induced apoptosis in Jurkat, a leukemic T cell line, is enhanced by ceramide

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Bioavailability of curcumin: problems and promises

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Modulation of carcinoembryonic antigen release by glucosylceramide. Implications for HT29 cell differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-1086-9

21 January 2018

Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of D-[3H]threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-phenyl-2-decanoylamino-3-morpholino-1-propanol chemosensitizes neuroblastoma cells for taxol and vincristine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide activates heterotrimeric protein phosphatase 2A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and the dilemma of cancer chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21959977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-011-1086-9

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

release_afgyy6ebrjhsbdzpj7ykdsbuce

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https://api.fatcat.wiki/v0/release/afgyy6ebrjhsbdzpj7ykdsbuce

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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