Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells (Q39472164)

12 September 2017

Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells (English)

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12 September 2017

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K Taketani

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12 September 2017

J Kawauchi

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12 September 2017

M Tanaka-Okamoto

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12 September 2017

H Ishizaki

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Y Tanaka

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12 September 2017

T Sakai

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12 September 2017

J Miyoshi

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Y Maehara

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S Kitajima

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12 September 2017

language of work or name

English

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publication date

19 September 2011

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12 September 2017

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31

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2210-2221

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https://scigraph.springernature.com/pub.10.1038/onc.2011.397

12 September 2017

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To kill a tumor cell: the potential of proapoptotic receptor agonists

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Irinotecan in the treatment of colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

21 January 2018

The Hallmarks of Cancer

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Identification of LRF-1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription

21 January 2018

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Plat-E: an efficient and stable system for transient packaging of retroviruses

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Oncogenic Ras sensitizes normal human cells to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis

21 January 2018

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From bench to clinic with apoptosis-based therapeutic agents

21 January 2018

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ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

The expression of transcription factor activating transcription factor 3 in the human prostate and its regulation by androgen in prostate cancer

21 January 2018

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

21 January 2018

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An atlas of combinatorial transcriptional regulation in mouse and man

21 January 2018

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Transcriptional control of human p53-regulated genes

21 January 2018

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A histopathological assessment of the response of rectal adenocarcinoma to combination chemo-radiotherapy: relationship to apoptotic activity, p53 and bcl-2 expression.

21 January 2018

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Apoptosis and cancer drug targeting

21 January 2018

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Caspase-10 is an initiator caspase in death receptor signaling

21 January 2018

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Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.

21 January 2018

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Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway.

21 January 2018

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A global map of p53 transcription-factor binding sites in the human genome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Identification and characterization of a new member of the TNF family that induces apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Opposing roles for calcineurin and ATF3 in squamous skin cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

A potential dichotomous role of ATF3, an adaptive-response gene, in cancer development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Transcriptional activation of the human stress-inducible transcriptional repressor ATF3 gene promoter by p53.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

A matter of life and death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2011.397

Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2011.397

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.397

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12 September 2017

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