Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis (Q39474971)

12 September 2017

title

Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis (English)

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12 September 2017

7

Yabing Chen

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12 September 2017

Gu Jing

1

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12 September 2017

Kaiyu Yuan

2

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12 September 2017

Qiuli Liang

3

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12 September 2017

Yong Sun

4

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12 September 2017

Xia Mao

5

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12 September 2017

Jay M McDonald

6

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12 September 2017

publication date

12 September 2011

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12 September 2017

published in

Laboratory Investigation

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12 September 2017

volume

92

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12 September 2017

issue

1

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12 September 2017

page(s)

82-90

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https://scigraph.springernature.com/pub.10.1038/labinvest.2011.131

12 September 2017

exact match

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cites work

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Apoptosis and tumorigenesis in human cholangiocarcinoma cells. Involvement of Fas/APO-1 (CD95) and calmodulin

21 January 2018

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Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein

21 January 2018

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The combination of calmodulin antagonists and interferon-gamma induces apoptosis through caspase-dependent and -independent pathways in cholangiocarcinoma cells.

21 January 2018

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Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma).

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IFN-gammaupregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma

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Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis

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Differential recruitment of caspase 8 to cFlip confers sensitivity or resistance to Fas-mediated apoptosis in a subset of familial lymphoma patients

21 January 2018

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Inhibition of death receptor signals by cellular FLIP

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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Casper is a FADD- and caspase-related inducer of apoptosis

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The CD95(APO-1/Fas) DISC and beyond

21 January 2018

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c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

21 January 2018

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The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

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Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.

21 January 2018

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Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

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Three-dimensional structure of calmodulin

21 January 2018

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The Fas-induced apoptosis analyzed by high throughput proteome analysis

21 January 2018

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Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK).

21 January 2018

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Calmodulin binding to the Fas death domain. Regulation by Fas activation

21 January 2018

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Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling

21 January 2018

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Biliary adenocarcinoma. Characterisation of three new human tumor cell lines.

21 January 2018

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Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Development of a novel trans-lentiviral vector that affords predictable safety

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Dominant-negative Fas mutation is reversed by down-expression of c-FLIP.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

The relevance of NF-kappaB for CD95 signaling in tumor cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

CaMBOT: profiling and characterizing calmodulin-binding proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

c-FLIPR, a new regulator of death receptor-induced apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Activation of NF-kappaB by FADD, Casper, and caspase-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

Cholangiocarcinomas express Fas ligand and disable the Fas receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

inferred from DOI database lookup

7 January 2021

based on heuristic

Fas engagement accelerates liver regeneration after partial hepatectomy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.131

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LABINVEST.2011.131

1 reference

Dimensions Publication ID

12 September 2017

1052303740

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1 reference