MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. (Q39483441)

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11 February 2020

title

MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation (English)

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11 February 2020

3

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11 February 2020

author name string

Jun Yang

1

1 reference

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11 February 2020

Shengying Qin

2

1 reference

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11 February 2020

Gang Ma

4

1 reference

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11 February 2020

Huang Zhu

5

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11 February 2020

Wenrong Zhou

6

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11 February 2020

Yuyu Xiong

7

1 reference

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11 February 2020

Xuming Zhu

8

1 reference

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11 February 2020

Yujiong Wang

9

1 reference

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11 February 2020

Lin He

10

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11 February 2020

Xizhi Guo

11

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11 February 2020

language of work or name

English

0 references

publication date

26 August 2011

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11 February 2020

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11 February 2020

volume

585

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11 February 2020

issue

19

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11 February 2020

page(s)

2992-2997

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

11 February 2020

cites work

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Interactions between Sox9 and beta-catenin control chondrocyte differentiation

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Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

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MicroRNA-140 plays dual roles in both cartilage development and homeostasis

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Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development

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Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT

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Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level.

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Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

21 January 2018

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Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation.

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The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells

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