Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells. (Q39500848)

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8 February 2020

title

Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells (English)

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8 February 2020

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5

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8 February 2020

Javier Turnay

6

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8 February 2020

author name string

Juan Ignacio Barrasa

1

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8 February 2020

Nieves Olmo

2

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8 February 2020

Pablo Pérez-Ramos

3

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8 February 2020

Angélica Santiago-Gómez

4

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8 February 2020

M Antonia Lizarbe

7

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publication date

1 October 2011

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8 February 2020

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8 February 2020

volume

16

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issue

10

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8 February 2020

page(s)

1054-1067

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https://scigraph.springernature.com/pub.10.1007/s10495-011-0633-x

8 February 2020

exact match

0 references

cites work

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Protection of human colon epithelial cells against deoxycholate by rottlerin

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Effect of high fat consumption on cell proliferation activity of colorectal mucosa and on soluble faecal bile acids

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Bile acids as carcinogens in human gastrointestinal cancers

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Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line

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Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids

21 January 2018

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Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

21 January 2018

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The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.

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Genotoxic effect of bile acids on human normal and tumour colon cells and protection by dietary antioxidants and butyrate.

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Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.

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Effect of bile acids on butyrate-sensitive and -resistant human colon adenocarcinoma cells.

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Acquisition of resistance to butyrate induces resistance to luminal components and other types of stress in human colon adenocarcinoma cells

21 January 2018

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Establishment and characterization of a new human colon adenocarcinoma cell line: BCS-TC2.

21 January 2018

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Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis

21 January 2018

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Acquisition of resistance to butyrate enhances survival after stress and induces malignancy of human colon carcinoma cells.

21 January 2018

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Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase.

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Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5.

21 January 2018

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Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

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Caspase-3 is required in the apoptotic disintegration of the nuclear matrix

21 January 2018

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Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells.

21 January 2018

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p53 is cleaved by caspases generating fragments localizing to mitochondria

21 January 2018

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Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion

21 January 2018

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Bile-acid-induced cell injury and protection

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Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines

21 January 2018

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Deoxycholate induces mitochondrial oxidative stress and activates NF-kappaB through multiple mechanisms in HCT-116 colon epithelial cells

21 January 2018

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Bile salt-induced apoptosis in human colon cancer cell lines involves the mitochondrial transmembrane potential but not the CD95 (Fas/Apo-1) receptor

21 January 2018

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Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid

21 January 2018

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Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition

21 January 2018

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Bile acid induces hydrophobicity-dependent membrane alterations

21 January 2018

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Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

21 January 2018

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Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

21 January 2018

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Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1.

21 January 2018

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Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

21 January 2018

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Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations

21 January 2018

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10.1007/S10495-011-0633-X

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789651%20AND%20SRC:MED&resulttype=core&format=json

release_uq2itwnpfbar7nfokpuctdrily

8 February 2020

Fatcat ID

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24 November 2022

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