Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis (Q39505400)

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English	Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis	scientific article

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scholarly article

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Europe PubMed Central

12 September 2017

Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis (English)

1 reference

Europe PubMed Central

12 September 2017

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author name string

Julie M Roda

1

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Europe PubMed Central

12 September 2017

Laura A Sumner

2

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Europe PubMed Central

12 September 2017

Randall Evans

3

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Europe PubMed Central

12 September 2017

Gary S Phillips

4

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Europe PubMed Central

12 September 2017

Clay B Marsh

5

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Europe PubMed Central

12 September 2017

Timothy D Eubank

6

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Europe PubMed Central

12 September 2017

language of work or name

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publication date

15 July 2011

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12 September 2017

Journal of Immunology

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Europe PubMed Central

12 September 2017

187

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12 September 2017

4

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Europe PubMed Central

12 September 2017

1970-1976

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Europe PubMed Central

12 September 2017

Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150377

12 September 2017

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

1 reference

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Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

1 reference

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Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages

1 reference

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

1 reference

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Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling

1 reference

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HIF-1alpha is essential for myeloid cell-mediated inflammation

1 reference

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

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Granulocyte-macrophage colony-stimulating factor alone or with dacarbazine in metastatic melanoma: a randomized phase II trial

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Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

1 reference

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12 September 2017

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

1 reference

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Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

1 reference

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Characterisation of macrophages infiltrating human mammary carcinomas

1 reference

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In aged mice, outgrowth of intraocular melanoma depends on proangiogenic M2-type macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150377

14 September 2017

Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150377

14 September 2017

A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150377

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Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages

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GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150377

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Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

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Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

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Clinicopathological implications of tumour-associated macrophages and vascularization in sinonasal melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer

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https://pubmed.ncbi.nlm.nih.gov/21765015

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Detection of circulating melanoma cells by RT-PCR amplification of three different melanocyte-specific mRNAs in a mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Prognostic value of serum VEGF in melanoma patients: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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inferred from PubMed ID database lookup

GM-CSF up-regulates the expression of CCL2 by T lymphocytes in mammary tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21765015

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Identifiers

10.4049/JIMMUNOL.1100841

1 reference

Europe PubMed Central

12 September 2017

release_5yu3yojqrjec7cw5icnpudozte

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1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

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