Functional significance of Aurora kinase A regulatory interactions with p53-ERα complex in human breast cancer cells (Q39506267)

12 September 2017

title

Functional significance of Aurora kinase A regulatory interactions with p53-ERα complex in human breast cancer cells (English)

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12 September 2017

Hiroshi Katayama

1

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12 September 2017

Subrata Sen

series ordinal

2

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12 September 2017

publication date

1 April 2011

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12 September 2017

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12 September 2017

volume

2

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12 September 2017

issue

2

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12 September 2017

page(s)

117-124

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Aurora-A - a guardian of poles

12 September 2017

cites work

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

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Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

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The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

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Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

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Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis

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Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy

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Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells.

21 January 2018

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Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer

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Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

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Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex

21 January 2018

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Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

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Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets

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Polymorphisms of the AURKA (STK15/Aurora Kinase) Gene and Breast Cancer Risk (United States).

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p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis

21 January 2018

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Transcriptional control of human p53-regulated genes

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Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells

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Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation.

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Defining the Steps in a Multistep Mouse Model for Mammary Carcinogenesis

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P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

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Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle

21 January 2018

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Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells.

21 January 2018

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Estrogen-dependent and independent activation of the P1 promoter of the p53 gene in transiently transfected breast cancer cells

21 January 2018

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12 December 2020

Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast

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12 December 2020

Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer.

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12 December 2020

P53 expression in breast cancer

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12 December 2020

Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer.

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12 December 2020

Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast.

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12 December 2020

P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis

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12 December 2020

10.1007/S12672-011-0070-X

Identifiers

DOI

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12 September 2017

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