Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. (Q39521282)

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scientific article published on 7 November 2006

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English	Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion.	scientific article published on 7 November 2006

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21 December 2019

Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion (English)

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21 December 2019

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Steven M. Wolinsky

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21 December 2019

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Elaine R Thomas

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21 December 2019

Rebecca L Dunfee

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Jennifer Stanton

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Derek Bogdan

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Joann Taylor

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Kevin Kunstman

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Jeanne E Bell

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Dana Gabuzda

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7 November 2006

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360

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21 December 2019

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

1 reference

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Mechanisms of HIV-1 neurotropism

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Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes

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Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

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CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity

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Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

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Concordant utilization of macrophage entry coreceptors by related variants within an HIV type 1 primary isolate viral swarm

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25 September 2017

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

25 September 2017

A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

25 September 2017

Preparation and characterization of human HIV type 1 neutralizing reference sera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

25 September 2017

HIV dementia and the basal ganglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

HIV type 1 V3 sequences and the development of dementia during AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

AIDS dementia complex and HIV-1 brain infection: clinical-virological correlations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Variations in CD4 expression by human monocytes and macrophages and their relationships to infection with the human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

HIV receptors within the brain: a study of CD4 and MHC-II on human neurons, astrocytes and microglial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Early viral brain invasion in iatrogenic human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Signature pattern analysis: a method for assessing viral sequence relatedness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

17 June 2018

Genetic attributes of cerebrospinal fluid-derived HIV-1 env.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Marked improvement in survival following AIDS dementia complex in the era of highly active antiretroviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

HIV-related neuropathology, 1985 to 1999: rising prevalence of HIV encephalopathy in the era of highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Chemokine receptors in the brain: their role in HIV infection and pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

CD4 T cell surface CCR5 density as a host factor in HIV-1 disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Independent evolution of HIV type 1 in different brain regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Expression and characterization of HIV type 1 envelope protein associated with a broadly reactive neutralizing antibody response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Gp120 sequence variation in brain and in T-lymphocyte human immunodeficiency virus type 1 primary isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

Unique HIV type 1 V3 region sequences derived from six different regions of brain: region-specific evolution within host-determined quasispecies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

21 August 2018

HIV-1 tropism and co-receptor use

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

1 October 2018

Surface CD4 Is Critical to in Vitro HIV Infection of Human Alveolar Macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890014

2 December 2018

Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

Opposite Effects of IL-10 on the Ability of Dendritic Cells and Macrophages to Replicate Primary CXCR4-Dependent HIV-1 Strains

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

Chemokine receptor regulation and HIV type 1 tropism in monocyte-macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

HIV-associated neurologic disease incidence changes:: Multicenter AIDS Cohort Study, 1990-1998

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

HIV-associated cognitive impairment before and after the advent of combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.09.036

7 January 2021

Distinct HIV-1 env sequences are associated with neurotropism and neurovirulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/17084877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.VIROL.2006.09.036

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17084877%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17084877%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17084877%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

ResearchGate publication ID

0 references

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