Vorinostat, SAHA, represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells. (Q39523550)

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scientific article published on October 2011

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English	Vorinostat, SAHA, represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells.	scientific article published on October 2011

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scholarly article

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5 February 2020

Vorinostat, SAHA, represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells (English)

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5 February 2020

non-small-cell lung carcinoma

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based on heuristic

inferred from title

6

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5 February 2020

author name string

Chien-Te Li

1

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5 February 2020

Yi-Min Hsiao

2

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5 February 2020

Tzu-Chin Wu

3

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5 February 2020

Yu-Wen Lin

4

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5 February 2020

Kun-Tu Yeh

5

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publication date

1 October 2011

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5 February 2020

Journal of Cellular Biochemistry

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5 February 2020

112

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5 February 2020

10

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5 February 2020

3044-3053

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5 February 2020

Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances gemcitabine-induced cell death in pancreatic cancer

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Novel Hydroxamate and Anilide Derivatives as Potent Histone Deacetylase Inhibitors: Synthesis and Antiproliferative Evaluation

1 reference

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21 January 2018

TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116.

1 reference

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21 January 2018

Histone Deacetylase Inhibitors: The Abbott Experience

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Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells

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21 January 2018

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

1 reference

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21 January 2018

MethyLight: a high-throughput assay to measure DNA methylation

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Telomere Length and Telomerase Activity in Bladder and Prostate Cancer Cell Lines

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Telomerase as a therapeutic target for malignant gliomas.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms

1 reference

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21 January 2018

The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

A phase II trial of vorinostat (suberoylanilide hydroxamic acid) in metastatic breast cancer: a California Cancer Consortium study

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Histone deacetylase inhibitors: Potential in cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Histone deacetylases and cancer: causes and therapies

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Vorinostat increases carboplatin and paclitaxel activity in non-small-cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

The cancer epigenome--components and functional correlates

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Distinct and temporal roles of nucleosomal remodeling and histone deacetylation in the repression of the hTERT gene

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

ErbB-3 expression is associated with E-cadherin and their coexpression restores response to gefitinib in non-small-cell lung cancer (NSCLC).

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas

1 reference

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21 January 2018

hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23229

21 January 2018

Identifiers

10.1002/JCB.23229

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21678477%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21678477%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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