Imidazolopiperazines: hit to lead optimization of new antimalarial agents. (Q39530026)

PubMed publication ID

21644570

12 September 2017

title

Imidazolopiperazines: hit to lead optimization of new antimalarial agents (English)

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31

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Thomas H. Keller

33

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Elizabeth Winzeler

35

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32

Veronique Dartois

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author name string

Tao Wu

1

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Advait Nagle

2

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Kelli Kuhen

3

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Kerstin Gagaring

4

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Rachel Borboa

5

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Caroline Francek

6

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Zhong Chen

7

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David Plouffe

8

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Anne Goh

9

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Suresh B Lakshminarayana

10

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Jeanette Wu

11

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Hui Qing Ang

12

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Peiting Zeng

13

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Min Low Kang

14

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William Tan

15

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Maria Tan

16

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Nicole Ye

17

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Xuena Lin

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Christopher Caldwell

19

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Jared Ek

20

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Suzanne Skolnik

21

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Fenghua Liu

22

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Jianling Wang

23

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Jonathan Chang

24

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Chun Li

25

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Thomas Hollenbeck

26

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Tove Tuntland

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John Isbell

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Christoph Fischli

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Reto Brun

30

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Thierry Diagana

34

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Richard Glynne

36

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David C Tully

37

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Arnab K Chatterjee

38

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language of work or name

English

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publication date

23 June 2011

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PubMed publication ID

21644570

Journal of Medicinal Chemistry

12 September 2017

published in

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volume

54

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issue

14

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page(s)

5116-5130

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High throughput assay technologies for ion channel drug discovery.

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cites work

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Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles

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Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum

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Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

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Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials

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Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

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Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes

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Identifiers

DOI

10.1021/JM2003359

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6950218&resulttype=core&format=json

13 May 2020

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13 May 2020

PubMed publication ID

21644570

1 reference