Cisplatin increases B-cell-lymphoma-2 expression via activation of protein kinase C and Akt2 in endometrial cancer cells (Q39535128)

12 September 2017

Cisplatin increases B-cell-lymphoma-2 expression via activation of protein kinase C and Akt2 in endometrial cancer cells (English)

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12 September 2017

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Alexandre Rouette

1

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12 September 2017

Sophie Parent

2

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12 September 2017

Julie Girouard

3

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12 September 2017

Valérie Leblanc

4

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12 September 2017

Eric Asselin

5

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12 September 2017

language of work or name

English

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publication date

5 August 2011

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International Journal of Cancer

12 September 2017

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12 September 2017

130

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12 September 2017

1755-1767

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12 September 2017

8

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12 September 2017

Cancer statistics, 2009

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The resurgence of platinum-based cancer chemotherapy

21 January 2018

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Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

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Bcl-2 family proteins and cancer

21 January 2018

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Protein kinase C isoforms: Multi-functional regulators of cell life and death

21 January 2018

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Phase I study of bryostatin 1, a protein kinase C modulator, preceding cisplatin in patients with refractory non-hematologic tumors

21 January 2018

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PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Calpha-mediated Bcl-2 stabilization

21 January 2018

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Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death

21 January 2018

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

21 January 2018

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 January 2018

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 January 2018

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Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer

21 January 2018

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Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

21 January 2018

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Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site.

21 January 2018

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

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Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

21 January 2018

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Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol

21 January 2018

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TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha

21 January 2018

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Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

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Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis.

21 January 2018

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AKT involvement in cisplatin chemoresistance of human uterine cancer cells

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

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Differential expression of antiapoptotic genes in human endometrial carcinoma: bcl-XL succeeds bcl-2 function in neoplastic cells

21 January 2018

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Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation.

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

21 January 2018

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Analysis of protein kinase C delta (PKC delta) expression in endometrial tumors

21 January 2018

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Endometrial cancer cell survival and apoptosis is regulated by protein kinase C alpha and delta

21 January 2018

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Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy

21 January 2018

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Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis

21 January 2018

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Cisplatin: mode of cytotoxic action and molecular basis of resistance

21 January 2018

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Influence of the proto-oncogene c-fos on cisplatin sensitivity

21 January 2018

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Anti-apoptotic effects of protein kinase C-delta and c-fos in cisplatin-treated thyroid cells.

21 January 2018

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Differential response of normal, dedifferentiated and transformed thyroid cell lines to cisplatin treatment

21 January 2018

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Differential functions of PKC-delta and PKC-zeta in cisplatin response of normal and transformed thyroid cells.

21 January 2018

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

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The role of protein kinase C in cell surface signal transduction and tumour promotion

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.26183

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12 September 2017

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