Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4. (Q39543340)

12 September 2017

Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4. (English)

1 reference

12 September 2017

J B Jones

1

1 reference

PMCID

102729

12 September 2017

S E Kern

series ordinal

2

1 reference

PMCID

102729

12 September 2017

language of work or name

English

0 references

publication date

1 June 2000

1 reference

12 September 2017

Nucleic Acids Research

1 reference

12 September 2017

28

1 reference

12 September 2017

2363-2368

1 reference

12 September 2017

12

1 reference

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Human Smad3 and Smad4 are sequence-specific transcription activators

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

A structural basis for mutational inactivation of the tumour suppressor Smad4

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Dpc4 transcriptional activation and dysfunction in cancer cells.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

A human Mad protein acting as a BMP-regulated transcriptional activator

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102729

DPC4 gene in various tumor types

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10871368

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10871368

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/28.12.2363

1 reference

12 September 2017

1 reference

12 September 2017

1 reference

PMCID

102729