Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate i (Q39546982)

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scientific article published on August 2011

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English	Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate i	scientific article published on August 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 September 2017

Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate i (English)

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12 September 2017

Ana Maria Da Costa Ferreira

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Ana Maria Da Costa Ferreira

3

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Giuseppe Filomeni

1

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Europe PubMed Central

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12 September 2017

Simone Cardaci

2

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12 September 2017

Giuseppe Rotilio

4

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12 September 2017

Maria Rosa Ciriolo

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12 September 2017

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publication date

1 August 2011

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12 September 2017

Biochemical Journal

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12 September 2017

437

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12 September 2017

3

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12 September 2017

443-453

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Europe PubMed Central

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12 September 2017

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Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage

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The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis

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Identifiers

10.1042/BJ20110510

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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