Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein. (Q39551896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9971808%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein (English)

1 reference

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11 December 2019

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3

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11 December 2019

author name string

König C

series ordinal

1

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Roth J

series ordinal

2

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11 December 2019

language of work or name

English

0 references

publication date

1 March 1999

1 reference

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11 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9971808%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

volume

73

1 reference

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issue

3

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11 December 2019

page(s)

2253-2262

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9971808%20AND%20SRC:MED&resulttype=core&format=json

p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus

11 December 2019

cites work

1 reference

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14 September 2017

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Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

14 September 2017

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Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.

14 September 2017

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Assembly of complete, functionally active herpes simplex virus DNA replication compartments and recruitment of associated viral and cellular proteins in transient cotransfection assays.

14 September 2017

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The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells.

14 September 2017

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The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

14 September 2017

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

14 September 2017

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Deletion of the E4 region of the genome produces adenovirus DNA concatemers

14 September 2017

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Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs.

14 September 2017

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Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

14 September 2017

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Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

14 September 2017

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p53 modulation of TFIIH-associated nucleotide excision repair activity

14 September 2017

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Expression of adenovirus-2 early region 4: assignment of the early region 4 polypeptides to their respective mRNAs, using in vitro translation

14 September 2017

1 reference

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Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

14 September 2017

1 reference

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Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

14 September 2017

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The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs

14 September 2017

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Identification of two nuclear subclasses of the adenovirus type 5-encoded DNA-binding protein

14 September 2017

1 reference

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Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport

14 September 2017

1 reference

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Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids

14 September 2017

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Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection

14 September 2017

1 reference

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Suppression of human colorectal carcinoma cell growth by wild-type p53

14 September 2017

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Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

14 September 2017

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Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

14 September 2017

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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

14 September 2017

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Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

14 September 2017

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Inhibition of HeLa cell protein synthesis during adenovirus infection. Restriction of cellular messenger RNA sequences to the nucleus

14 September 2017

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Intracistronic complementation reveals a new function of SV40 T antigen that co-operates with Rb and p53 binding to stimulate DNA synthesis in quiescent cells

14 September 2017

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

25 September 2017

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25 September 2017

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25 September 2017

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The intracellular distribution of the transformation-associated protein p53 in adenovirus-transformed rodent cells.

15 June 2018

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Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies.

15 June 2018

1 reference

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Transactivation of the p53 oncogene by E1a gene products

15 June 2018

1 reference

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The human cytomegalovirus IE2 86 kDa protein elevates p53 levels and transactivates the p53 promoter in human fibroblasts.

15 June 2018

1 reference

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Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

21 August 2018

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A monoclonal antibody detecting the adenovirus type 5-E1b-58Kd tumor antigen: characterization of the E1b-58Kd tumor antigen in adenovirus-infected and -transformed cells

21 August 2018

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Identification of intranuclear structures containing the 72K DNA-binding protein of human adenovirus type 5

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9971808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9971808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9971808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.73.3.2253-2262.1999

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9971808%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference