Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance. (Q39565163)

From Wikidata

Jump to navigation Jump to search

scientific article published on April 2011

Language	Label	Description	Also known as
English	Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance.	scientific article published on April 2011

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

0 references

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

Francesco Andreozzi

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Gaia Chiara Mannino

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Gregoryalexander Raciti

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

C Procopio

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

A Greco

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

C Miele

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

C Iadicicco

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

F Beguinot

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

A E Pontiroli

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

M L Hribal

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

publication date

1 April 2011

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

54

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1879-1887

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21461637%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-011-2116-6

0 references

Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Pathophysiology of insulin resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Critical nodes in signalling pathways: insights into insulin action

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Physiological and molecular determinants of insulin action in the baboon.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2116-6

21 January 2018

Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PHLPPing it off: phosphatases get in the Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-receptor kinase activity of adipose tissue from morbidly obese humans with and without NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis and Classification of Diabetes Mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from Type II diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired autophosphorylation of insulin receptors from abdominal skeletal muscles in nonobese subjects with NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laparoscopic adjustable gastric banding for the treatment of morbid (grade 3) obesity and its metabolic complications: a three-year study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21461637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39565163&oldid=1767185519"