A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania (Q39604692)

13 September 2017

A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania (English)

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13 September 2017

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GeneDB

ABC transporter, putative

5 February 2019

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GeneDB

6 February 2019

ABC transporter, putative

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hypothetical protein, conserved

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José María Pérez-Victoria

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author

object named as

José M Pérez-Victoria

7

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Ignacio Pérez-Victoria

object named as

Ignacio Pérez-Victoria

4

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Francisco Gamarro

object named as

Francisco Gamarro

6

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author name string

Jenny Campos-Salinas

1

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13 September 2017

María Cabello-Donayre

2

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13 September 2017

Raquel García-Hernández

3

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13 September 2017

Santiago Castanys

5

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13 September 2017

language of work or name

English

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publication date

23 January 2011

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13 September 2017

Molecular Microbiology

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13 September 2017

79

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13 September 2017

1430-1444

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13 September 2017

6

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Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

13 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The role of half-transporters in multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The Genome of the African Trypanosome Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

ABCG2 transports and transfers heme to albumin through its large extracellular loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

ABC efflux pump-based resistance to chemotherapy drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

ABC Transporters: From Microorganisms to Man

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The genome of the kinetoplastid parasite, Leishmania major

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Antileishmanial drug development: exploitation of parasite heme dependency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The role of transporters in cellular heme and porphyrin homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

ATP-binding cassette, subfamily G (ABCG family).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Review. Structure and mechanism of ATP-binding cassette transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Metabolism of Leishmania: proven and predicted

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Biochemical and molecular mechanisms of drug resistance in parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Leishmaniasis: drugs in the clinic, resistance and new developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Leishmania requires Rab7-mediated degradation of endocytosed hemoglobin for their growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Purification of breast cancer resistance protein ABCG2 and role of arginine-482.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The product of the YCR105 gene located on the chromosome III from Saccharomyces cerevisiae presents homologies to ATP-dependent permeases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The leishmania ARL-1 and Golgi traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The role of ATP-binding cassette (ABC) proteins in protozoan parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Trafficking of heme and porphyrins in metazoa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Rab5-mediated endosome-endosome fusion regulates hemoglobin endocytosis in Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Heme and virulence: how bacterial pathogens regulate, transport and utilize heme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

Heme as a source of iron to Leishmania infantum amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07531.X

10.1111/J.1365-2958.2010.07531.X

21 January 2018

Identifiers

DOI

1 reference

13 September 2017

1 reference