Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas (Q39606000)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21246394%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas (English)

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20 January 2020

11

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Mark W. Kieran

13

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10

Patrick Y Wen

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20 January 2020

5

Eva Fast

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20 January 2020

author name string

Deviney Chaponis

1

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20 January 2020

Jessica W Barnes

2

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20 January 2020

Jamie L Dellagatta

3

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20 January 2020

Santosh Kesari

4

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20 January 2020

Claire Sauvageot

6

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20 January 2020

Dipak Panagrahy

7

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20 January 2020

Emily R Greene

8

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20 January 2020

Naren Ramakrishna

9

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20 January 2020

Charles Stiles

12

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20 January 2020

publication date

19 January 2011

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Journal of Neuro-Oncology

20 January 2020

published in

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volume

104

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20 January 2020

issue

1

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20 January 2020

page(s)

179-189

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describes a project that uses

20 January 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s11060-010-0502-4

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The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity

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21 August 2018

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21 August 2018

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21 August 2018

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12 December 2020

Ras regulation of radioresistance in cell culture

1 reference

12 December 2020

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines

1 reference

12 December 2020

SCH66336, inhibitor of protein farnesylation, blocks signal transducer and activators of transcription 3 signaling in lung cancer and interacts with a small molecule inhibitor of epidermal growth factor receptor/human epidermal growth factor recepto

1 reference

12 December 2020

10.1007/S11060-010-0502-4

Identifiers

DOI

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20 January 2020

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20 January 2020

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