Role of orexin A signaling in dietary palmitic acid-activated microglial cells (Q39623518)

13 September 2017

Role of orexin A signaling in dietary palmitic acid-activated microglial cells (English)

1 reference

13 September 2017

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26306651%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Joshua P Nixon

6

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1 June 2020

author name string

Cayla M Duffy

1

1 reference

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1 June 2020

Lauren E Wisdorf

3

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1 June 2020

Charles J Billington

4

1 reference

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1 June 2020

Catherine M Kotz

5

1 reference

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1 June 2020

Tammy A Butterick

7

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1 June 2020

language of work or name

English

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publication date

22 August 2015

1 reference

13 September 2017

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1 June 2020

volume

606

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1 June 2020

page(s)

140-144

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26306651%20AND%20SRC:MED&resulttype=core&format=json

Microglial M1/M2 polarization and metabolic states

1 June 2020

cites work

1 reference

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Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.

14 September 2017

1 reference

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Hypothalamic microinflammation: a common basis of metabolic syndrome and aging

14 September 2017

1 reference

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Fractalkine regulation of microglial physiology and consequences on the brain and behavior

14 September 2017

1 reference

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Orexin-A promotes cell migration in cultured rat astrocytes via Ca2+-dependent PKCα and ERK1/2 signals

14 September 2017

1 reference

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Obesity and neuroinflammation: a pathway to cognitive impairment

14 September 2017

1 reference

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Microglial priming in neurodegenerative disease

14 September 2017

1 reference

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Orexin: pathways to obesity resistance?

14 September 2017

1 reference

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Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

14 September 2017

1 reference

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Parkinson's disease in the nuclear age of neuroinflammation.

14 September 2017

1 reference

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Neuroinflammation and neurodegeneration in overnutrition-induced diseases

14 September 2017

1 reference

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Brain orexin promotes obesity resistance.

14 September 2017

1 reference

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Orexin A decreases lipid peroxidation and apoptosis in a novel hypothalamic cell model

14 September 2017

1 reference

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OX2R activation induces PKC-mediated ERK and CREB phosphorylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Obesity is associated with hypothalamic injury in rodents and humans

14 September 2017

1 reference

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Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling

14 September 2017

1 reference

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Microglial interactions with synapses are modulated by visual experience

14 September 2017

1 reference

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Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

14 September 2017

1 reference

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Brain foods: the effects of nutrients on brain function

14 September 2017

1 reference

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ATP mediates rapid microglial response to local brain injury in vivo

14 September 2017

1 reference

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Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion.

17 June 2018

1 reference

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Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Palmitic acid is associated with halorhodopsin as a free fatty acid. Radiolabeling of halorhodopsin with 3H-palmitic acid and chemical analysis of the reaction products of purified halorhodopsin with thiols and NaBH4.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

17 June 2018

1 reference

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High fat diet induces specific pathological changes in hypothalamic orexin neurons in mice.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Neuroinflammatory phenotypes and their roles in Alzheimer's disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Characterization of cellular and neurological damage following unilateral hypoxia/ischemia

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811357

Orexins promote survival of rat cortical neurons

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26306651

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEULET.2015.08.033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26306651%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26306651%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26306651%20AND%20SRC:MED&resulttype=core&format=json