Ceramide Produces Apoptosis Through Induction of p27kip1by Protein Phosphatase 2A-dependent Akt Dephosphorylation in PC-3 Prostate Cancer Cells (Q39643015)

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scientific article published on January 1, 2010

Language	Label	Description	Also known as
English	Ceramide Produces Apoptosis Through Induction of p27kip1by Protein Phosphatase 2A-dependent Akt Dephosphorylation in PC-3 Prostate Cancer Cells	scientific article published on January 1, 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Ceramide produces apoptosis through induction of p27(kip1) by protein phosphatase 2A-dependent Akt dephosphorylation in PC-3 prostate cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Ceramide Produces Apoptosis Through Induction of p27kip1by Protein Phosphatase 2A-dependent Akt Dephosphorylation in PC-3 Prostate Cancer Cells (English)

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

1 reference

based on heuristic

inferred from title

prostate cancer

1 reference

based on heuristic

inferred from title

author name string

Sang Woo Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Hae Jong Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Young Jin Chun

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Mie Young Kim

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20954073

4 August 2024

publication date

1 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

full work available at URL

http://www.tandfonline.com/doi/pdf/10.1080/15287394.2010.511553

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

Journal of Toxicology and Environmental Health Part A

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Europe PubMed Central

PubMed publication ID

13 September 2017

73

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Europe PubMed Central

PubMed publication ID

13 September 2017

21-22

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Europe PubMed Central

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13 September 2017

1465-1476

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Europe PubMed Central

PubMed publication ID

13 September 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Functions of ceramide in coordinating cellular responses to stress

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

PP2A: the expected tumor suppressor

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Bax-dependent apoptosis induced by ceramide in HL-60 cells

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Potent inhibition of recombinant human cytochrome p-450 1A1 by pentamethoxystilbene

1 reference

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21 January 2018

p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Regulation of protein kinase cascades by protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Ceramide in apoptosis: an overview and current perspectives

1 reference

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21 January 2018

Phosphoinositide-3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells.

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

PI3K/Akt signaling regulates p27(kip1) expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27(kip1) regulation in LNCaP and PC346 cells

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death.

1 reference

https://api.crossref.org/works/10.1080%2F15287394.2010.511553

21 January 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

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21 January 2018

BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells

1

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer

2

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

Okadaic acid, useful tool for studying cellular processes

7

1 reference

10.1080/15287394.2010.511553

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4 August 2024

Differential gene expression by styrene in rat reproductive tissue

10

1 reference

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4 August 2024

Involvement of p27(kip1) in ceramide-mediated apoptosis in HL-60 cells

15

1 reference

10.1080/15287394.2010.511553

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4 August 2024

Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain

16

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

Inhibition of protein synthesis in a cell-free system and Vero cells by okadaic acid, a diarrhetic shellfish toxin

20

1 reference

10.1080/15287394.2010.511553

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4 August 2024

Programmed cell death induced by ceramide

25

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Induction of p21 during ceramide-mediated apoptosis in human hepatocarcinoma cells

26

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4 August 2024

Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A

30

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10.1080/15287394.2010.511553

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Activation of de novo synthetic pathway of ceramides is responsible for the initiation of hydrogen peroxide-induced apoptosis in HL-60 cells

34

1 reference

10.1080/15287394.2010.511553

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4 August 2024

Cancer Research

35

58

542

author name string

Tsihlias J.

publication date

1998

1 reference

10.1080/15287394.2010.511553

https://api.crossref.org/works/10.1080/15287394.2010.511553

4 August 2024

Identifiers

10.1080/15287394.2010.511553

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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