Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901 (Q39644047)

13 September 2017

title

Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901 (English)

1 reference

https://api.crossref.org/works/10.1016/J.BIOPHA.2010.08.008

phosphoinositide-3 kinase inhibitor

2 August 2024

main subject

NF-κB

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20947290

2 August 2024

author name string

Xu Chao

1

1 reference

13 September 2017

Jiang Zao

2

1 reference

13 September 2017

Gu Xiao-Yi

3

1 reference

13 September 2017

Meng Li-Jun

4

1 reference

13 September 2017

Shi Tao

5

1 reference

13 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20947290

2 August 2024

publication date

23 September 2010

1 reference

full work available at URL

13 September 2017

https://api.elsevier.com/content/article/PII:S0753332210001356?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BIOPHA.2010.08.008

https://api.elsevier.com/content/article/PII:S0753332210001356?httpAccept=text/plain

2 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.BIOPHA.2010.08.008

Biomedicine and Pharmacotherapy

2 August 2024

published in

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13 September 2017

volume

64

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13 September 2017

issue

9

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13 September 2017

page(s)

600-604

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The activation of Akt/PKB signaling pathway and cell survival.

13 September 2017

cites work

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Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

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Structure, regulation and function of NF-kappa B

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Increased expression of NF-kappa B subunits in human pancreatic cancer cells

2 August 2024

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Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

2 August 2024

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Simvastatin induces apoptosis in human breast cancer cells in a NFkappaB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa

2 August 2024

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Adenovirus-uteroglobin suppresses COX-2 expression via inhibition of NF-kappaB activity in lung cancer cells

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

2 August 2024

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

2 August 2024

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

2 August 2024

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus

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NF-kappaB at the crossroads of life and death

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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Frequent mutation of the PIK3CA gene in ovarian and breast cancers

2 August 2024

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Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines

2 August 2024

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Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients

2 August 2024

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Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

2 August 2024

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Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product

2 August 2024

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p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

2 August 2024

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Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis

2 August 2024

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PI3K/Akt inhibition modulates multidrug resistance and activates NF-kappaB in murine lymphoma cell lines.

2 August 2024

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Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways

2 August 2024

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1,25-dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB.

2 August 2024

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2 August 2024

Identifiers

1 reference

release_h26nmjcp7rcztcozxzxnnlfr64

13 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h26nmjcp7rcztcozxzxnnlfr64

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference