Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells. (Q39652589)

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14 February 2020

title

Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells (English)

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14 February 2020

0 references

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chronic lymphocytic leukemia

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6

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14 February 2020

author name string

M Suljagic

1

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14 February 2020

L Laurenti

2

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14 February 2020

M Tarnani

3

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14 February 2020

M Alam

4

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14 February 2020

S N Malek

5

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publication date

23 September 2010

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14 February 2020

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14 February 2020

volume

24

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issue

12

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page(s)

2063-2071

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Recent advances in the molecular biology and immunobiology of chronic lymphocytic leukemia.

14 February 2020

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PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

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PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

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Identifiers

DOI

10.1038/LEU.2010.201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20861921%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference