The alpha2delta ligand gabapentin inhibits the Rab11-dependent recycling of the calcium channel subunit alpha2delta-2. (Q39652650)

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14 February 2020

title

The alpha2delta ligand gabapentin inhibits the Rab11-dependent recycling of the calcium channel subunit alpha2delta-2 (English)

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14 February 2020

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2

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14 February 2020

Alexandra Tran-Van-Minh

series ordinal

1

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language of work or name

English

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publication date

1 September 2010

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14 February 2020

published in

Journal of Neuroscience

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14 February 2020

volume

30

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14 February 2020

issue

38

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14 February 2020

page(s)

12856-12867

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describes a project that uses

14 February 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding

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12 December 2020

Structure and regulation of voltage-gated Ca2+ channels

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12 December 2020

Differential effect of gabapentin on neuronal and muscle calcium currents.

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12 December 2020

Calcium channel alpha(2)delta subunits-structure and Gabapentin binding

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12 December 2020

Rab4 affects both recycling and degradative endosomal trafficking

1 reference

12 December 2020

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

1 reference

12 December 2020

Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase

1 reference

12 December 2020

Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury

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12 December 2020

Gabapentin is not a GABAB receptor agonist

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12 December 2020

The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function

1 reference

12 December 2020

Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones

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12 December 2020

Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression.

1 reference

12 December 2020

The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.

1 reference

12 December 2020

Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases

1 reference

12 December 2020

Long-term regulation of voltage-gated Ca(2+) channels by gabapentin

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12 December 2020

Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere

1 reference

12 December 2020

Auxiliary subunits: essential components of the voltage-gated calcium channel complex.

1 reference

12 December 2020

Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C

1 reference

12 December 2020

Does gabapentin act as an agonist at native GABA(B) receptors?

1 reference

12 December 2020

Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene.

1 reference

12 December 2020

Spinal dorsal horn calcium channel alpha2delta-1 subunit upregulation contributes to peripheral nerve injury-induced tactile allodynia

1 reference

12 December 2020

Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors

1 reference

12 December 2020

Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro.

1 reference

12 December 2020

The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of alpha2delta subunits is key to trafficking voltage-gated Ca2+ channels

1 reference

12 December 2020

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane

1 reference

12 December 2020

Kinetics of internalization and degradation of N-type voltage-gated calcium channels: role of the alpha2/delta subunit

1 reference

12 December 2020

Calcium channel alpha2delta1 subunit mediates spinal hyperexcitability in pain modulation

1 reference

12 December 2020

The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.

1 reference

12 December 2020

Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking

1 reference

12 December 2020

Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin

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12 December 2020

Complement and the multifaceted functions of VWA and integrin I domains

1 reference

12 December 2020

Molecular anatomy of a trafficking organelle

1 reference

12 December 2020

Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels

1 reference

12 December 2020

Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels

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12 December 2020

Immunocytochemistry and quantification of protein colocalization in cultured neurons

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12 December 2020

Image averaging of flexible fibrous macromolecules: The clathrin triskelion has an elastic proximal segment

1 reference

12 December 2020

Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin

1 reference

12 December 2020

PKC-induced intracellular trafficking of Ca(V)2 precedes its rapid recruitment to the plasma membrane

1 reference

12 December 2020

Rab GTPases and their roles in brain neurons and glia

1 reference

12 December 2020

Time course and specificity of the pharmacological disruption of the trafficking of voltage-gated calcium channels by gabapentin

1 reference

12 December 2020

Functional properties and modulation of extracellular epitope-tagged Ca(V)2.1 voltage-gated calcium channels.

1 reference

12 December 2020

Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag

1 reference

12 December 2020

The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

1 reference

12 December 2020

Rab GTPases as coordinators of vesicle traffic

1 reference

12 December 2020

Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes

1 reference

12 December 2020

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis

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12 December 2020

Endocytosis of glycosylphosphatidylinositol-anchored proteins

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12 December 2020

The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

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12 December 2020

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

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12 December 2020

Use of site-directed antibodies to probe the topography of the alpha 2 subunit of voltage-gated Ca2+ channels

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12 December 2020

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1

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12 December 2020

A somatodendritic distribution of Rab11 in rabbit brain neurons

1 reference

12 December 2020

Isolation of the [3H]gabapentin-binding protein/alpha 2 delta Ca2+ channel subunit from porcine brain: development of a radioligand binding assay for alpha 2 delta subunits using [3H]leucine

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12 December 2020

Host cell-specific folding of the neuronal nicotinic receptor alpha8 subunit

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12 December 2020

Molecular diversity of the calcium channel alpha2delta subunit

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12 December 2020

10.1523/JNEUROSCI.2700-10.2010

Identifiers

DOI

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14 February 2020

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14 February 2020

PubMed publication ID

20861389

1 reference