Pathogenic lysosomal depletion in Parkinson's disease (Q39655523)

13 September 2017

Pathogenic lysosomal depletion in Parkinson's disease (English)

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13 September 2017

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7

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15 May 2020

Benjamin Dehay

1

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15 May 2020

Natalia Rodríguez-Muela

3

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Ariadna Recasens

5

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15 May 2020

Patricia Boya

6

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15 May 2020

author name string

Jordi Bové

2

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15 May 2020

Celine Perier

4

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language of work or name

English

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publication date

1 September 2010

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13 September 2017

Journal of Neuroscience

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15 May 2020

volume

30

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15 May 2020

issue

37

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15 May 2020

page(s)

12535-12544

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Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

15 May 2020

cites work

1 reference

12 December 2020

The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers

1 reference

12 December 2020

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

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12 December 2020

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

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12 December 2020

Targeting programmed cell death in neurodegenerative diseases

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12 December 2020

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Sucrose-induced vacuolation results in increased expression of cholesterol biosynthesis and lysosomal genes

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12 December 2020

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 reference

12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

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12 December 2020

Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

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12 December 2020

Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

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12 December 2020

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12 December 2020

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

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12 December 2020

Loss of autophagy in the central nervous system causes neurodegeneration in mice

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12 December 2020

Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle

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12 December 2020

Glucocerebrosidase mutations are an important risk factor for Lewy body disorders.

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12 December 2020

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

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12 December 2020

Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease.

1 reference

12 December 2020

Calpain is required for macroautophagy in mammalian cells

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12 December 2020

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

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12 December 2020

Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death

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12 December 2020

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

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12 December 2020

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

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12 December 2020

How to interpret LC3 immunoblotting

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12 December 2020

Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death

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12 December 2020

Lysosomes: fusion and function

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12 December 2020

ROS, mitochondria and the regulation of autophagy

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12 December 2020

Ultrastructure of Lewy bodies in the stellate ganglion

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12 December 2020

Autophagy: process and function

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12 December 2020

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

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12 December 2020

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

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12 December 2020

Autophagy in the Pathogenesis of Disease

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12 December 2020

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

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12 December 2020

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

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12 December 2020

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

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12 December 2020

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

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12 December 2020

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

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12 December 2020

Mitochondrial alterations in Parkinson's disease: new clues

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12 December 2020

Lysosomal membrane permeabilization in cell death

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12 December 2020

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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12 December 2020

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

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12 December 2020

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

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12 December 2020

A gene network regulating lysosomal biogenesis and function

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12 December 2020

Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein

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12 December 2020

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

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12 December 2020

Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease

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12 December 2020

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

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12 December 2020

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

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12 December 2020

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

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12 December 2020

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

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12 December 2020

Lysosomal biogenesis in lysosomal storage disorders

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12 December 2020

10.1523/JNEUROSCI.1920-10.2010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

15 May 2020

1 reference