Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer. (Q39660739)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20811155%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer (English)

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13 February 2020

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7

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13 February 2020

Roelof Koster

1

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13 February 2020

Anke van den Berg

5

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13 February 2020

Albert J.H. Suurmeijer

6

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13 February 2020

Jourik A. Gietema

8

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13 February 2020

3

Hetty Timmer-Bosscha

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13 February 2020

author name string

Alessandra di Pietro

2

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13 February 2020

Johan H Gibcus

4

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13 February 2020

Steven de Jong

9

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13 February 2020

language of work or name

English

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publication date

1 September 2010

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Journal of Clinical Investigation

13 February 2020

published in

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13 February 2020

volume

120

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13 February 2020

issue

10

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13 February 2020

page(s)

3594-3605

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The biological effects of isoform-specific PI3-kinase inhibition

13 February 2020

cites work

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Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids

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Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo

14 September 2017

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A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

14 September 2017

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Testicular germ-cell cancer.

14 September 2017

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Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors

14 September 2017

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Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures

14 September 2017

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Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity

14 September 2017

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Testicular germ cell tumours: the paradigm of chemo-sensitive solid tumours

14 September 2017

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A microRNA polycistron as a potential human oncogene

14 September 2017

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Testicular germ-cell tumours in a broader perspective.

14 September 2017

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Somatic mutations of KIT in familial testicular germ cell tumours

14 September 2017

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

14 September 2017

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Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines

14 September 2017

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Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death

14 September 2017

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

14 September 2017

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.

14 September 2017

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Low p21Waf1/Cip1 protein level sensitizes testicular germ cell tumor cells to Fas-mediated apoptosis.

14 September 2017

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Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation

14 September 2017

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Differential effects of all-trans-retinoic acid, docosahexaenoic acid, and hexadecylphosphocholine on cisplatin-induced cytotoxicity and apoptosis in a cisplantin-sensitive and resistant human embryonal carcinoma cell line.

25 September 2017

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Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines.

25 September 2017

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25 September 2017

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Deregulation of the RB pathway in human testicular germ cell tumours

25 September 2017

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Germ cell tumors of the testis overexpress wild-type p53.

15 June 2018

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cis-diamminedichloroplatinum(ii) resistance in vitro and in vivo in human embryonal carcinoma cells.

15 June 2018

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15 June 2018

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AKT signaling promotes derivation of embryonic germ cells from primordial germ cells

21 August 2018

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21 August 2018

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21 August 2018

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Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line.

21 August 2018

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Cdk2 activity is associated with depolarization of mitochondrial membrane potential during apoptosis

21 August 2018

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Expression of the PDGF alpha-receptor 1.5 kb transcript, OCT-4, and c-KIT in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms

21 August 2018

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Transition from in situ to invasive testicular germ cell neoplasia is associated with the loss of p21 and gain of mdm-2 expression.

21 August 2018

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International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group

21 August 2018

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Cell cycle regulators in testicular cancer: loss of p18INK4C marks progression from carcinoma in situ to invasive germ cell tumours

1 October 2018

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12 December 2020

Cyclin A/cdk2 activation is involved in hypoxia-induced apoptosis in cardiomyocytes

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12 December 2020

Immunohistochemical and mutational analysis of the p53 tumour suppressor gene and the bcl-2 oncogene in primary testicular germ cell tumours

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12 December 2020

Biology and genetics of adult male germ cell tumors

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12 December 2020

Role of the urologist in metastatic testicular cancer

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12 December 2020

Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells

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12 December 2020

Identifiers

DOI

10.1172/JCI41939

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20811155%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20811155%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20811155

1 reference