Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. (Q39665315)

13 September 2017

Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. (English)

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13 September 2017

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Francisco J. Quintana

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object named as

Francisco J Quintana

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13 September 2017

Jenny Aurielle B Babon

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Jenny Aurielle B Babon

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13 September 2017

Ada Yeste

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Maisa C Takenaka

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Ivan D Mascanfroni

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Meghan Nadeau

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Jessica E Kenison

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Bonny Patel

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Ann-Marcia Tukpah

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Megan DeNicola

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Sally C Kent

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David Pozo

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21 June 2016

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ra61

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Genetics, pathogenesis and clinical interventions in type 1 diabetes

13 September 2017

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Immune mechanisms in type 1 diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Regulatory T cells: mechanisms of differentiation and function

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

FOXP3+ regulatory T cells in the human immune system

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Analysis of islet inflammation in human type 1 diabetes.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Type 1 diabetes: translating mechanistic observations into effective clinical outcomes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Breakdown in peripheral tolerance in type 1 diabetes in mice and humans

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Autologous regulatory T cells for the treatment of type 1 diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

It's time to bring dendritic cell therapy to type 1 diabetes.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Immune therapy in type 1 diabetes mellitus

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Immune intervention in type 1 diabetes.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Dietary ligands of the aryl hydrocarbon receptor induce anti-inflammatory and immunoregulatory effects on murine dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Antigen targets of type 1 diabetes autoimmunity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Gold, the noble metal and the paradoxes of its toxicology

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Pancreatic islet-specific T-cell clones from nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Chromogranin A is an autoantigen in type 1 diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

The role of dendritic cells in autoimmunity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Development and function of dendritic cell subsets

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Role and therapeutic value of dendritic cells in central nervous system autoimmunity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Aryl hydrocarbon receptor control of adaptive immunity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

21 January 2018

LeA(H)Rning self-control

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

SOCS2-induced proteasome-dependent TRAF6 degradation: a common anti-inflammatory pathway for control of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

A cluster of coregulated genes determines TGF-beta-induced regulatory T-cell (Treg) dysfunction in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Reversal of autoimmunity by boosting memory-like autoregulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Dendritic cell-dependent in vivo generation of autoregulatory T cells by antidiabetogenic MHC class II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

T cells enhance gold nanoparticle delivery to tumors in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Suppressor of cytokine signaling 1 (SOCS1) limits NFkappaB signaling by decreasing p65 stability within the cell nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Antigen-specific therapeutic approaches in Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0612

10.1126/SCISIGNAL.AAD0612

21 January 2018

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DOI

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13 September 2017

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