Can single knockouts accurately single out gene functions? (Q39667259)

13 September 2017

Can single knockouts accurately single out gene functions? (English)

1 reference

13 September 2017

4

Eytan Ruppin

1 reference

13 September 2017

3

Stefan Schuster

1 reference

13 September 2017

David Deutscher

1

1 reference

PMCID

2443110

13 September 2017

Isaac Meilijson

series ordinal

2

1 reference

13 September 2017

18 June 2008

1 reference

13 September 2017

1 reference

13 September 2017

2

1 reference

13 September 2017

50

1 reference

https://scigraph.springernature.com/pub.10.1186/1752-0509-2-50

13 September 2017

0 references

cites work

Harnessing naturally randomized transcription to infer regulatory relationships among genes

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Systematic condition-dependent annotation of metabolic genes

14 September 2017

1 reference

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Inferring functional pathways from multi-perturbation data

14 September 2017

1 reference

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Quantitative analysis of genetic and neuronal multi-perturbation experiments

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Metabolic functions of duplicate genes in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Expanded metabolic reconstruction of Helicobacter pylori (iIT341 GSM/GPR): an in silico genome-scale characterization of single- and double-deletion mutants

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Regulatory on/off minimization of metabolic flux changes after genetic perturbations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Fair attribution of functional contribution in artificial and biological networks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Global mapping of the yeast genetic interaction network

14 September 2017

1 reference

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Systematic genome-wide screens of gene function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Advances in flux balance analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Genome-scale microbial in silico models: the constraints-based approach.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Analysis of optimality in natural and perturbed metabolic networks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Functional profiling of the Saccharomyces cerevisiae genome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Test of synergistic interactions among deleterious mutations in bacteria

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Averaging attributable fractions in the multifactorial situation: assumptions and interpretation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Axiomatic scalable neurocontroller analysis via the Shapley value.

17 June 2018

1 reference

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Modular epistasis in yeast metabolism.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Fair localization of function via multi-lesion analysis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Optimization-based framework for inferring and testing hypothesized metabolic objective functions.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Inferring subnetworks from perturbed expression profiles

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443110

Multiple knockout analysis of genetic robustness in the yeast metabolic network

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18564419

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural robustness of metabolic networks with respect to multiple knockouts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18564419

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1752-0509-2-50

1 reference

journals/bmcsb/DeutscherMSR08

13 September 2017

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

13 September 2017

1 reference

PMCID

2443110