In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice. (Q39683616)

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scientific article published on 7 July 2010

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English	In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice.	scientific article published on 7 July 2010

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scholarly article

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7 February 2020

In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice (English)

1 reference

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7 February 2020

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1

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7 February 2020

6

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7 February 2020

author name string

Miriam Perez

2

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7 February 2020

Rebeca Real

3

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7 February 2020

Estefania Egido

4

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7 February 2020

Julio G Prieto

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7 February 2020

publication date

7 July 2010

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7 February 2020

Pharmaceutical Research

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7 February 2020

27

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7 February 2020

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7 February 2020

2098-2105

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7 February 2020

Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response.

1 reference

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21 January 2018

The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).

1 reference

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Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Inhibitory effects of herbal extracts on breast cancer resistance protein (BCRP) and structure-inhibitory potency relationship of isoflavonoids.

1 reference

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12 December 2020

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In vitro and in vivo interaction of moxidectin with BCRP/ABCG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk

1 reference

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12 December 2020

based on heuristic

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Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Dose translation from animal to human studies revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin t

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Effect of pregnancy on nitrofurantoin disposition in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bioavailability of the isoflavone biochanin A in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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ABCG2: a perspective.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Intestinal and hepatic glucuronidation of flavonoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Metabolic phenotype of isoflavones differ among female rats, pigs, monkeys, and women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Lack of an inducible effect of dietary soy isoflavones on the mRNA abundance of hepatic cytochrome P-450 isozymes in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Differential effects of chrysin on nitrofurantoin pharmacokinetics mediated by intestinal breast cancer resistance protein in rats and mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Absolute bioavailability of isoflavones from soy protein isolate-containing food in female BALB/c mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

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Efficacy of isoflavones in relieving vasomotor menopausal symptoms - A systematic review

1 reference

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12 December 2020

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Characterization of substrates and inhibitors for the in vitro assessment of Bcrp mediated drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human ABC transporter ABCG2 in cancer chemotherapy and pharmacogenomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin

1 reference

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ABC transporters and isothiocyanates: potential for pharmacokinetic diet-drug interactions

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of flavonoids via enteric recycling: structural effects and lack of correlations between in vitro and in situ metabolic properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent absorption, metabolism, and excretion of genistein in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoid-drug interactions: effects of flavonoids on ABC transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic effects of oral genistein administration in neonatal mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of soy isoflavones in normal human breast tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commentary: bioavailability of flavonoids and polyphenols: call to arms

1 reference

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Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies

1 reference

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Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607366

12 December 2020

based on heuristic

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Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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