F18, a novel small-molecule nonnucleoside reverse transcriptase inhibitor, inhibits HIV-1 replication using distinct binding motifs as demonstrated by resistance selection and docking analysis. (Q39692280)

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scientific article published on 28 October 2011

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English	F18, a novel small-molecule nonnucleoside reverse transcriptase inhibitor, inhibits HIV-1 replication using distinct binding motifs as demonstrated by resistance selection and docking analysis.	scientific article published on 28 October 2011

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scholarly article

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15 January 2020

F18, a novel small-molecule nonnucleoside reverse transcriptase inhibitor, inhibits HIV-1 replication using distinct binding motifs as demonstrated by resistance selection and docking analysis (English)

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15 January 2020

Stephen Kwok-Wing Tsui

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Xiaofan Lu

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Li Liu

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Xu Zhang

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Terrence Chi Kong Lau

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Yuanxi Kang

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Purong Zheng

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Bojian Zheng

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Gang Liu

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28 October 2011

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Antimicrobial Agents and Chemotherapy

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15 January 2020

The effect of highly active antiretroviral therapy on the survival of HIV-infected children in a resource-deprived setting: a cohort study

1 reference

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Retroviral reverse transcriptases

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1128/AAC.05537-11

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15 January 2020

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15 January 2020

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15 January 2020

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