E7 abolishes raf-induced arrest via mislocalization of p21(Cip1). (Q39695591)

14 September 2017

E7 abolishes raf-induced arrest via mislocalization of p21(Cip1). (English)

1 reference

14 September 2017

Thomas F Westbrook

1

1 reference

14 September 2017

Don X Nguyen

series ordinal

2

1 reference

14 September 2017

Barry R Thrash

series ordinal

3

1 reference

14 September 2017

Dennis J McCance

series ordinal

4

1 reference

14 September 2017

language of work or name

English

0 references

publication date

1 October 2002

1 reference

Molecular and Cellular Biology

14 September 2017

1 reference

14 September 2017

22

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14 September 2017

20

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14 September 2017

7041-7052

1 reference

describes a project that uses

14 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC139800/fullTextXML

inferred from PubMed Central ID database lookup

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14 September 2017

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14 September 2017

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Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity

14 September 2017

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New functional activities for the p21 family of CDK inhibitors

14 September 2017

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14 September 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

14 September 2017

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The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

14 September 2017

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Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc

14 September 2017

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Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.

14 September 2017

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Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

14 September 2017

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Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

14 September 2017

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14 September 2017

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Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation

14 September 2017

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

14 September 2017

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WAF1, a potential mediator of p53 tumor suppression

14 September 2017

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

14 September 2017

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Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

14 September 2017

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Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

14 September 2017

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

14 September 2017

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Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

14 September 2017

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14 September 2017

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

14 September 2017

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The retinoblastoma protein and cell cycle control

14 September 2017

1 reference

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Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Inhibition of cyclin-dependent kinases by p21

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

A point mutational analysis of human papillomavirus type 16 E7 protein

14 September 2017

1 reference

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

14 September 2017

1 reference

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Transforming collaborations between ras and nuclear oncogenes.

14 September 2017

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

14 September 2017

1 reference

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The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation

14 September 2017

1 reference

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Cooperation between oncogenes

14 September 2017

1 reference

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Induction of apoptosis in fibroblasts by c-myc protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein

14 September 2017

1 reference

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Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

14 September 2017

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

25 September 2017

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The biology of human papillomaviruses: from warts to cancer.

25 September 2017

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E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

p21-containing cyclin kinases exist in both active and inactive states

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139800

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

25 September 2017

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p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

25 September 2017

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The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

17 June 2018

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

17 June 2018

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p21 Is a Component of Active Cell Cycle Kinases

17 June 2018

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The E7 open reading frame of human papillomavirus type 16 encodes a transforming gene.

17 June 2018

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The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.

17 June 2018

1 reference

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Ability of the HPV16 E7 protein to bind RB and induce DNA synthesis is not sufficient for efficient transforming activity in NIH3T3 cells

17 June 2018

1 reference

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

17 June 2018

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Cooperating oncogenes converge to regulate cyclin/cdk complexes.

20 August 2018

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

20 August 2018

1 reference

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Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

20 August 2018

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12 December 2020

Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor

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12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

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12 December 2020

Cellular proteins that are targetted by DNA tumor viruses for transformation

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12 December 2020

10.1128/MCB.22.20.7041-7052.2002

Identifiers

DOI

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

12242284

1 reference