Insulin promotes survival of amyloid-beta oligomers neuroblastoma damaged cells via caspase 9 inhibition and Hsp70 upregulation. (Q39701747)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Insulin promotes survival of amyloid-beta oligomers neuroblastoma damaged cells via caspase 9 inhibition and Hsp70 upregulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Pasquale Picone

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Rita Carrotta

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Daniela Giacomazza

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Pier Luigi San Biagio

5

1 reference

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3 February 2020

author name string

M Di Carlo

1

1 reference

14 September 2017

P Picone

2

1 reference

14 September 2017

R Carrotta

3

1 reference

14 September 2017

D Giacomazza

4

1 reference

14 September 2017

P L San Biagio

5

1 reference

14 September 2017

13 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomedicine and Biotechnology

3 February 2020

published in

1 reference

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3 February 2020

volume

2010

1 reference

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3 February 2020

page(s)

147835

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

3 February 2020

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

The relationship between Alzheimer's disease and diabetes: Type 3 diabetes?

14 September 2017

1 reference

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Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

14 September 2017

1 reference

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Beta amyloid peptide: from different aggregation forms to the activation of different biochemical pathways.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

(Pre)diabetes, brain aging, and cognition

14 September 2017

1 reference

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Insulin resistance and Alzheimer's disease: molecular links & clinical implications.

14 September 2017

1 reference

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Protein misfolding, functional amyloid, and human disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

The activation of Akt/PKB signaling pathway and cell survival.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Signaling by insulin-like growth factor 1 in brain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

14 September 2017

1 reference

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The role of oxidative stress in diabetic vascular and neural disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Apoptosis and caspases in neurodegenerative diseases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

14 September 2017

1 reference

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Chaperoning brain degeneration

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

14 September 2017

https://pubmed.ncbi.nlm.nih.gov/20490276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hsp70 and antifibrillogenic peptides promote degradation and inhibit intracellular aggregation of amyloidogenic light chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Biology of A beta amyloid in Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Expression of heat shock proteins in Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression

17 June 2018

1 reference

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A presenilin 1 mutation (L420R) in a family with early onset Alzheimer disease, seizures and cotton wool plaques, but not spastic paraparesis

20 August 2018

1 reference

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Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Insulin inhibits amyloid beta-induced cell death in cultured human brain pericytes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

20 August 2018

1 reference

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Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871552

Toxicity of recombinant β-amyloid prefibrillar oligomers on the morphogenesis of the sea urchinParacentrotus lividus

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20490276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amyloid beta oligomers induce impairment of neuronal insulin receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20490276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2010/147835

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20490276%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

20490276

1 reference