Active-site residues of Escherichia coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions leading to novobiocin resistance (Q39731838)

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English	Active-site residues of Escherichia coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions leading to novobiocin resistance	scientific article

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scholarly article

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Europe PubMed Central

14 September 2017

Active-site residues of Escherichia coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions leading to novobiocin resistance (English)

1 reference

Europe PubMed Central

14 September 2017

Escherichia coli

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author name string

Christian H Gross

1

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Europe PubMed Central

14 September 2017

Jonathan D Parsons

2

1 reference

Europe PubMed Central

14 September 2017

Trudy H Grossman

3

1 reference

Europe PubMed Central

14 September 2017

Paul S Charifson

4

1 reference

Europe PubMed Central

14 September 2017

Steven Bellon

5

1 reference

Europe PubMed Central

14 September 2017

James Jernee

6

1 reference

Europe PubMed Central

14 September 2017

Maureen Dwyer

7

1 reference

Europe PubMed Central

14 September 2017

Stephen P Chambers

8

1 reference

Europe PubMed Central

14 September 2017

William Markland

9

1 reference

Europe PubMed Central

14 September 2017

Martyn Botfield

10

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Europe PubMed Central

14 September 2017

Scott A Raybuck

11

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Europe PubMed Central

14 September 2017

language of work or name

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publication date

1 March 2003

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14 September 2017

number of pages

10

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Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

14 September 2017

47

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Europe PubMed Central

14 September 2017

3

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Europe PubMed Central

14 September 2017

1037-1046

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Europe PubMed Central

14 September 2017

Mutation in the DNA gyrase A Gene of Escherichia coli that expands the quinolone resistance-determining region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999: role of target enzyme in mechanism of fluoroquinolone resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Locking the ATP-operated clamp of DNA gyrase: probing the mechanism of strand passage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

A model for the mechanism of strand passage by DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Probing the role of the ATP-operated clamp in the strand-passage reaction of DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Conversion of DNA gyrase into a conventional type II topoisomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Mutations in the B subunit of Escherichia coli DNA gyrase that affect ATP-dependent reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Isolation and characterization of Bacillus subtilis genes involved in siderophore biosynthesis: relationship between B. subtilis sfpo and Escherichia coli entD genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Identifying the catalytic residue of the ATPase reaction of DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Resistance to antibiotics mediated by target alterations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

An unusual mechanism for resistance to the antibiotic coumermycin A1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Energy coupling in DNA gyrase and the mechanism of action of novobiocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Isolation and characterisation of a strain carrying a conditional lethal mutation in the cou gene of Escherichia coli K12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

DNA gyrase action involves the introduction of transient double-strand breaks into DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

Mutations in DNA gyrase result in novobiocin resistance in halophilic archaebacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

14 September 2017

DNA gyrase as a drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

25 September 2017

Prevention of drug access to bacterial targets: permeability barriers and active efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

25 September 2017

Inactivation of antibiotics and the dissemination of resistance genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

25 September 2017

The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

25 September 2017

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

15 June 2018

Identification of a residue involved in transition-state stabilization in the ATPase reaction of DNA gyrase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

15 June 2018

gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

15 June 2018

Timely release of both replication forks from oriC requires modulation of origin topology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

20 August 2018

Locking the DNA gate of DNA gyrase: investigating the effects on DNA cleavage and ATP hydrolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

20 August 2018

Probing the two-gate mechanism of DNA gyrase using cysteine cross-linking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

20 August 2018

Bacterial topoisomerases, anti-topoisomerases, and anti-topoisomerase resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

20 August 2018

The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

20 August 2018

Probing the Binding of Coumarins and Cyclothialidines to DNA Gyrase†

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149296

2 December 2018

The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription 1 1J. Karn

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrolysis of ATP at Only One GyrB Subunit Is Sufficient to Promote Supercoiling by DNA Gyrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Interaction of Coumarin Antibiotics with Fragments of the DNA Gyrase B Protein†

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploiting Nucleotide Thiophosphates To Probe Mechanistic Aspects ofEscherichia coliDNA Gyrase†

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

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Coumermycin A1: A preferential inhibitor of replicative DNA synthesis in Escherichia coli. I. In vivo characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA dependence of the ATPase activity of DNA gyrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of fluoroquinolone resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

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Spontaneous cAMP-dependent derepression of gene expression in stationary phase plays a role in recombinant expression instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12604539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.47.3.1037-1046.2003

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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