mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III. (Q39783160)

14 September 2017

mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III. (English)

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14 September 2017

reactive oxygen species

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Aaron M Gusdon

1

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14 September 2017

Tatyana V Votyakova

series ordinal

2

1 reference

14 September 2017

Clayton E Mathews

series ordinal

3

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14 September 2017

language of work or name

English

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publication date

15 February 2008

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Journal of Biological Chemistry

14 September 2017

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14 September 2017

283

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14 September 2017

16

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14 September 2017

10690-10697

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Myocardial ischemia-reperfusion injury, antioxidant enzyme systems, and selenium: a review

14 September 2017

1 reference

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Mitochondrial DNA mutations and aging.

22 September 2017

1 reference

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Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Nuclear and mitochondrial interaction involving mt-Nd2 leads to increased mitochondrial reactive oxygen species production

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Modulation of the antioxidant defence as a factor in apoptosis.

22 September 2017

1 reference

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Reactive oxygen species in the neuropathogenesis of hypertension

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Supramolecular structure of the mitochondrial oxidative phosphorylation system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs

22 September 2017

1 reference

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Mitochondrial DNA mutations in human cancer

22 September 2017

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Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria

22 September 2017

1 reference

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The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

22 September 2017

1 reference

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Generation of superoxide by the mitochondrial Complex I.

22 September 2017

1 reference

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Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

22 September 2017

1 reference

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Extension of murine life span by overexpression of catalase targeted to mitochondria

22 September 2017

1 reference

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Mitochondria, oxidants, and aging

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Structure of a mitochondrial supercomplex formed by respiratory-chain complexes I and III

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Complex III releases superoxide to both sides of the inner mitochondrial membrane

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Mitochondrial Production of Oxygen Radical Species and the Role of Coenzyme Q as an Antioxidant

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Topology of superoxide production from different sites in the mitochondrial electron transport chain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Oxidant injury in coronary heart disease (Part-I).

22 September 2017

1 reference

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Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Elevated oxidative stress in models of normal brain aging and Alzheimer's disease

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Oxidative stress, caloric restriction, and aging

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Oxidative damage and mitochondrial decay in aging

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Biochemistry of oxygen toxicity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Oxidative stress as a mediator of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Downregulation of the antioxidant defence during glucocorticoid-mediated apoptosis.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Effect of melatonin treatment on oxygen consumption by rat liver mitochondria

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Production of reactive oxygen species by mitochondria: central role of complex III.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

The molecular morphology of bovine heart mitochondrial NADH----ubiquinone reductase. Native disulfide-linked subunits and rotenone-induced conformational changes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

The non‐equivalence of binding sites of coenzyme quinone and rotenone in mitochondrial NADH‐CoQ reductase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Species- and tissue-specific relationships between mitochondrial permeability transition and generation of ROS in brain and liver mitochondria of rats and mice.

20 August 2018

1 reference

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Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

mt-Nd2 Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes

20 August 2018

1 reference

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Detection of hydrogen peroxide with Amplex Red: interference by NADH and reduced glutathione auto-oxidation

20 August 2018

1 reference

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Association of a 5178C-->A (Leu237Met) polymorphism in the mitochondrial DNA with a low prevalence of myocardial infarction in Japanese individuals.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Localization of the site of oxygen radical generation inside the complex I of heart and nonsynaptic brain mammalian mitochondria.

20 August 2018

1 reference

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Longevity-associated mitochondrial DNA 5178 A/C polymorphism and blood pressure in the Japanese population

20 August 2018

1 reference

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Characterization of superoxide-producing sites in isolated brain mitochondria

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Assembly of Respiratory Complexes I, III, and IV into NADH Oxidase Supercomplex Stabilizes Complex I in Paracoccus denitrificans

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

Mitochondrial 5178A/C genotype is associated with acute myocardial infarction

20 August 2018

1 reference

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Superoxide mediates the actions of angiotensin II in the central nervous system.

20 August 2018

1 reference

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Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?

20 August 2018

1 reference

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Association of the mitochondrial DNA 5178 A/C polymorphism with serum lipid levels in the Japanese population

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447668

DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

20 August 2018

1 reference

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Antiatherogenic mitochondrial genotype in patients with type 2 diabetes

20 August 2018

1 reference

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Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).

20 August 2018

1 reference

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Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria.

20 August 2018

1 reference

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Oxidative stress and total antioxidant status in myocardial infarction

20 August 2018

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12 December 2020

Oxidative stress and atherosclerosis

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12 December 2020

Fatty acids decrease mitochondrial generation of reactive oxygen species at the reverse electron transport but increase it at the forward transport

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12 December 2020

Superoxide and nitric oxide: consequences of varying rates of production and consumption: a theoretical treatment

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12 December 2020

Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress

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12 December 2020

A mitochondrial genotype associated with the development of autoimmune-related type 1 diabetes

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12 December 2020

Identifiers

DOI

10.1074/JBC.M708801200

1 reference

14 September 2017

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14 September 2017

1 reference