Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells (Q39800328)

14 September 2017

Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells (English)

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14 September 2017

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13

Hermann M Schätzl

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14 September 2017

2

Sabine Gilch

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14 September 2017

14

Ina Vorberg

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14 September 2017

Christian Bach

1

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14 September 2017

Romina Rost

3

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14 September 2017

Alex D Greenwood

4

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14 September 2017

Marion Horsch

5

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14 September 2017

Glaucia N M Hajj

6

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14 September 2017

Susanne Brodesser

7

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14 September 2017

Axel Facius

8

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14 September 2017

Sandra Schädler

9

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14 September 2017

Konrad Sandhoff

10

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14 September 2017

Johannes Beckers

11

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14 September 2017

Christine Leib-Mösch

12

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14 September 2017

language of work or name

English

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publication date

11 September 2009

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Journal of Biological Chemistry

14 September 2017

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14 September 2017

284

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14 September 2017

45

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14 September 2017

31260-31269

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describes a project that uses

14 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2781524/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of an intracellular site of prion conversion

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A systems approach to prion disease

22 September 2017

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Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

22 September 2017

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Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation

22 September 2017

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Transcriptional stability of cultured cells upon prion infection

22 September 2017

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CpG and LPS can interfere negatively with prion clearance in macrophage and microglial cells

22 September 2017

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Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures

22 September 2017

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Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins

22 September 2017

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Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list?

22 September 2017

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Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments

22 September 2017

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Gene expression alterations in brains of mice infected with three strains of scrapie

22 September 2017

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The prion protein requires cholesterol for cell surface localization.

22 September 2017

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Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells

22 September 2017

1 reference

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Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology

22 September 2017

1 reference

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Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

22 September 2017

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Two-fold differences are the detection limit for determining transgene copy numbers in plants by real-time PCR

22 September 2017

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The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells.

22 September 2017

1 reference

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Squalestatin cures prion-infected neurons and protects against prion neurotoxicity.

22 September 2017

1 reference

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Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents

22 September 2017

1 reference

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Mammalian prion biology: one century of evolving concepts

22 September 2017

1 reference

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Guideline to reference gene selection for quantitative real-time PCR

22 September 2017

1 reference

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Prion diseases: from molecular biology to intervention strategies

22 September 2017

1 reference

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Regulation of stearoyl-CoA desaturases and role in metabolism

22 September 2017

1 reference

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Molecular and clinical classification of human prion disease

22 September 2017

1 reference

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Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Cholesterol in Alzheimer's disease and tauopathy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Identification of upregulated genes in scrapie-infected brain tissue

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Identification of differentially expressed genes in scrapie-infected mouse neuroblastoma cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Measurement of protein using bicinchoninic acid

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Molecular biology of prion diseases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

High resolution preparative column chromatographic system for gangliosides using DEAE-Sephadex and a new porus silica, Iatrobeads

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Transcriptional changes in the brains of cattle orally infected with the bovine spongiform encephalopathy agent precede detection of infectivity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Microanalysis of complex tissue lipids by high-performance thin-layer chromatography.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Systematic gene expression profiling of mouse model series reveals coexpressed genes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Simvastatin treatment prolongs the survival of scrapie-infected mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: microarray and proteomics analyses in cultured murine cortical neurons.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Simvastatin prolongs survival times in prion infections of the central nervous system.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Gene expression profiling of the preclinical scrapie-infected hippocampus

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Gene expression profiling of scrapie-infected brain tissue.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Cholesterol and Tau Protein - Findings in Alzheimer’s and Niemann Pick C’s Disease

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781524

Identification of central nervous system genes involved in the host response to the scrapie agent during preclinical and clinical infection

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19748890

12 December 2020

inferred from PubMed ID database lookup

The use of Sep-Pak C18 cartridges during the isolation of gangliosides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19748890

12 December 2020

inferred from PubMed ID database lookup

Neuropathology of prion diseases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19748890

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M109.004382

1 reference

14 September 2017

1 reference

14 September 2017

1 reference