The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage (Q39821354)

14 September 2017

The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage (English)

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14 September 2017

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E K Cassimere

1

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PubMed ID

19629135

14 September 2017

S Pyndiah

series ordinal

2

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PubMed ID

19629135

14 September 2017

D Sakamuro

series ordinal

3

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14 September 2017

24 July 2009

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Cell Death & Differentiation

14 September 2017

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14 September 2017

16

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14 September 2017

12

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14 September 2017

1641-1653

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https://scigraph.springernature.com/pub.10.1038/cdd.2009.98

14 September 2017

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cites work

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

E2F from adenovirus-infected cells binds cooperatively to DNA containing two properly oriented and spaced recognition sites

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

E1A transcription induction: enhanced binding of a factor to upstream promoter sequences

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

E2F and cell proliferation: a world turned upside down

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

E2F-1 induced apoptosis

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Life and death decisions by the E2F transcription factors

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

E2F - at the crossroads of life and death

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

New Myc-interacting proteins: a second Myc network emerges

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms.

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

The E2F family: specific functions and overlapping interests

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Signaling networks that link cell proliferation and cell fate

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Antioncogenic effect of adenovirus E1A in human tumor cells

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

E1a induces the expression of epithelial characteristics

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Evidence for a function of CtBP in epithelial gene regulation and anoikis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

A protein interaction map for cell polarity development.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

hob1+, the fission yeast homolog of Bin1, is dispensable for endocytosis or actin organization, but required for the response to starvation or genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Cell polarity proteins: common targets for tumorigenic human viruses

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https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Bin1 ablation increases susceptibility to cancer during aging, particularly lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.98

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.98

1 reference

14 September 2017

1 reference

PubMed ID

19629135